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Transferases are a collection of a large and diverse group of enzymes that specifically catalyze the transfer of one or more functional groups from one molecule (the donor) to another (the acceptor). A few transferases involved in this category include farnesyltransferase (FTase), diacylglycerol acyltransferase (DGAT) and catechol-O-methyltransferase (COMT). Ftase catalyzes the transfer of a farnesyl moiety to the cysteine terminal residue (the sulfhydryl cysteine of the CAAS motif)) of substrate proteins. DGAT catalyzes the final step of the triacylglycerol (TG) biosynthetic pathway, where diacylglycerol is esterified to produce TG. COMT catalyzes the methylation of catechol substrates utilizing S-adenosyl-L-methionine (SAM) as a methyl donor and generating O-methylated catechol and S-adenosyl-L-homocysteine.

Compare Products

  1. Cat.No. Product Name Information
  2. A4382 A922500 DGAT-1 inhibitor
  3. B6134 Amodiaquine dihydrochloride dihydrate histamine N-methyl transferase inhibitor
  4. C3463 BCATc Inhibitor 2 cytosolic BCAT (BCATc) inhibitor
  5. B5785 Cystamine dihydrochloride transglutaminase inhibitor
  6. A4381 FK866 (APO866) NAMPT inhibitor,non-competitive, highly specific
  7. C3203 FTase Inhibitor II Ftase inhibitor
  8. B5842 FTI 277 HCl FTase inhibitor
  9. B5602 GGsTop γ-glutamyl transpeptidase (GGT) inhibitor, novel and irreversible
  10. B5729 GPP 78 hydrochloride NAMPT inhibitor
  11. B3703 LB42708 Selective FTase inhibitor

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