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BACE

BACE (β-Secretase) is an aspartic-acid protease that cleaves the amyloid precursor protein (APP) and takes part in the generation of Amyloid β.

  1. Cat.No. Product Name Information
  2. A8465 LY2886721 LY2886721 is an orally-available, furothiazine-based inhibitor of b-amyloid protein cleaving enzyme (BACE) for the treatment of Alzheimer's disease.
  3. B6195 Verubecestat (MK-8931)
  4. B5951 AZD3839
  5. B3224 AZD3839 AZD3839 is a novel inhibitor of BACE1 with IC50 value of 4.8μM .

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