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Apoptosis

Apoptosis

Apoptosis, also known as programed cell death, is a tightly controlled cellular process which is characterized by membrane blebbing, cell shrinkage, chromatin condensation, and DNA fragmentation.

RTK Rrk Receptor Akt PI3K

Products for  Apoptosis

  1. Cat.No. Product Name Information
  2. B6023 PD-1/PD-L1 inhibitor 2 PD-1/PD-L1 interaction inhibitor
  3. A3523 Kaempferol Apoptosis inducer;antioxidant;flavonoid
  4. A1902 Z-VAD-FMK Top Seller Cell-permeable, irreversible pan-caspase inhibitor
  5. A9901 Caspase Inhibitor Set I Caspase Inhibitors
  6. A1901 Q-VD-OPh hydrate Top Seller Cell-permeable, irreversible pan-caspase inhibitor
  7. A1925 Caspase-3/7 Inhibitor I Top Seller Caspase-3/7 inhibitor
  8. A8955 Z-YVAD-FMK Caspase-1 inhibitor
  9. A1921 Z-DQMD-FMK Top Seller Caspase-3 inhibitor,cell-permeable
  10. A1922 Z-VDVAD-FMK Top Seller Caspase-2 inhibitor
  11. A1923 Z-VEID-FMK Top Seller Caspase-6 inhibitor
  12. A1920 Z-DEVD-FMK Top Seller Caspase-3 inhibitor
  13. A8238 VX-765 Caspase-1 inhibitor,potent and selective
  14. A8165 Q-VD(OMe)-OPh Top Seller Pan-caspase inhibitor
  15. A8177 PAC-1 Top Seller Procaspase-3 activator
  16. B3233 Z-LEHD-FMK Irreversible Caspase-9 inhibitor.
  17. B3232 Z-IETD-FMK Caspase-8 inhibitor
  18. A1930 Apoptosis Inhibitor Top Seller Associate with caspase-3 inhibition
  19. A1924 Z-WEHD-FMK Caspase 5 inhibitor,potent,cell-permeable and irreversible
  20. A1904 Boc-D-FMK Pan-caspase inhibitor
  21. A4016 Apoptosis Activator 2 Indoledione caspase activator, cell-permeable
  22. A4418 Ac-IEPD-AFC Recognition motif for serine protease granzyme B
  23. A8321 Cisplatin Top Seller Inhibits DNA synthesis,chemotherapy drug
  24. A8170 Z-FA-FMK Top Seller Cysteine proteases inhibitor
  25. A4419 Ac-LEHD-AFC Fluorogenic caspase substrate
  26. A3424 Gambogic Acid Caspase activator and apoptosis inducer
  27. A4416 AZ 10417808 Caspase-3 inhibitor,selective non-peptide
  28. A4417 Ivachtin Caspase-3 inhibitor
  29. A4420 PETCM Caspase-3 activator
  30. B4618 Emricasan
  31. A4446 R18 14.3.3 proteins Antagonist
  32. A4234 TW-37 Top Seller Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1
  33. A3327 Costunolide Apoptosis inducer
  34. B4782 Epibrassinolide Potential apoptosis inducer;steroidal plant growth stimulant
  35. B7760 CFM 4 New Product
  36. A1984 Bendamustine HCl Cytostatic agent for non-Hodgkin lymphomas
  37. A8244 Cycloheximide Antibiotic,inhibiter of protein synthesis in eukaryotes
  38. A4453 NSC 687852 (b-AP15) 19S regulatory particle Inhibitor
  39. A4452 Mitomycin C Inhibits DNA synthesis,antibiotic and antitumor agent
  40. A3237 Betulinic acid Anti-HIV and antitumor compound,pentacyclic triterpenoid
  41. A3218 BAM7 BAX activator,direct and selective
  42. A4188 2-Methoxyestradiol (2-MeOE2) Apoptotic, antiproliferative and antiangiogenic agent
  43. A8176 Apicidin Potent HDAC inhibitor
  44. N1719 Kaempferol Apoptosis inducer;antioxidant;flavonoid
  45. A3118 3,3'-Diindolylmethane Anticancer and antineoplastic agent
  46. A3265 Brassinolide Plant growth regulator
  47. A3278 Capsaicin TRPV1 receptor agonist
  48. A3335 Curcumin Tyrosinase inhibitor
  49. A3583 Matrine Alkaloid found in Sophora plant
  50. A3746 R1530 Antiangiogenesis,mitosis-angiogenesis inhibitor (MAI)
  51. A3826 SMIP004 Apoptosis inducer;downre
  52. A3886 Trabectedin Antitumour agent
  53. B4760 Raltegravir potassium salt Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
  54. B1228 PM00104 Zalypsis(PM00104) is an alkaloid analog to certain natural marine compound. Zalyps is a potent antimyeloma agent with IC50 values from picomolar to low nanomolar ranges.
  55. B3255 Meisoindigo Apoptosis inducer;potential agent for AML
  56. A4448 Actinomycin D RNA polymerase inhibitor
  57. A4447 2,3-DCPE hydrochloride Bcl-XL protein expression downregulator
  58. A4449 C 75 Fatty acid synthase (FAS) inhibitor
  59. A4450 CHM 1 Tubulin polymerization inhibitor
  60. A8188 Atractyloside Dipotassium Salt ANT inhibitor
  61. A4451 Deguelin Anticancer and antiviral agent
  62. A4454 Oncrasin 1 Proapoptotic agent
  63. A4457 Streptozocin Antibiotic and antitumor agent
  64. A4455 Piperlongumine Inducer of cell-death
  65. A4456 Plumbagin Anticancer agent
  66. A4484 PRIMA-1MET Top Seller Restore mutant p53 activity, induce BAX and PUMA
  67. A4459 Bax channel blocker Inhibitor of Bax-mediated mitochondrial cytochrome c release
  68. A4483 PRIMA-1 Top Seller BAX inhibitor
  69. A4460 Bax inhibitor peptide P5 Bax inhibitor
  70. A4461 Bax inhibitor peptide V5 Bax inhibitor
  71. A4462 Bax inhibitor peptide, negative control Peptide inhibit Bax translocation to mitochondria
  72. A3935 WEHI-539 Bcl-xL inhibitor,potent and selective
  73. B6094 BH3I-1 Bcl-2 or Bcl-XL inhibitor
  74. A8737 S63845 MCL1 inhibitor
  75. B6011 A-1210477 MCL-1 inhibitor
  76. B5978 BDA-366 Selective antagonist of BCL2 BH4 domain
  77. B5846 Radotinib(IY-5511) Bcl-Abl tyrosine kinase inhibitor
  78. B4902 (+)-Apogossypol
  79. A8194 ABT-199 Bcl-2 inhibitor,potent and selective
  80. A8193 ABT-737 Top Seller Bcl-2 inhibitor
  81. A3007 ABT-263 (Navitoclax) Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w
  82. A9902 Bcl Family Set I Bcl family inhibitors
  83. B4881 UMI-77 Mcl-1 inhibitor, novel
  84. B4901 Pyridoclax
  85. A4194 Obatoclax mesylate (GX15-070) Potent Bcl-2 inhibitor
  86. A8168 HA14-1 Top Seller Bcl-2 inhibitor,potent and cell-permeable
  87. A4198 BM-1074 Bcl-2/Bcl-xL inhibitor,potent and selective
  88. A4200 Apogossypolone (ApoG2) Bcl-2 inhibitor,nonpeptidic small molecule
  89. A4199 Sabutoclax pan-Bcl-2 inhibitor
  90. B1080 Marinopyrrole A Selective Mcl-1 inhibitor
  91. A4463 BIM, Biotinylated Bim peptide fragment with a biotin moiety attached
  92. A4464 iMAC2 MAC inhibitor
  93. A4465 MIM1 Mcl-1 Inhibitor
  94. A4466 Muristerone A TRAIL- and hFasL-induced apoptosis inhibitor
  95. N2135 Gossypol PAF inhibitor;anti-fertility and anti-cancer
  96. A3196 AT-101 BH3-mimetic,gossypol enantiomer
  97. B4691 Mcl1-IN-1 Myeloid cell factor 1 inhibitor
  98. A8634 WEHI-539 hydrochloride Bcl-xL inhibitor,high affinity and selective
  99. A3847 SU5416 VEGF receptor inhibitor and AHR agonist
  100. A4237 Amuvatinib (MP-470, HPK 56) Top Seller Tyrosine kinase inhibitor
  101. A4116 Danusertib (PHA-739358) Top Seller Pan-aurora kinase inhibitor
  102. A4145 TG101209 Top Seller JAK2/3 inhibitor
  103. A8236 Regorafenib Top Seller Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
  104. A3750 Regorafenib hydrochloride Tyrosine kinase inhibitor
  105. A3751 Regorafenib monohydrate Tyrosine kinase inhibitor
  106. A3891 Triptolide IL-2/MMP-3/MMP7/MMP19 inhibitor
  107. A3019 AT-406 (SM-406) IAP inhibitor
  108. A8815 SM-164 Anticancer agent
  109. A4221 YM155 Survivin suppressant,apoptosis inhibitor
  110. A4219 Birinapant (TL32711) Potent XIAP/cIAP1 antagonist
  111. A8235 Embelin XIAP inhibitor,cell-permeable
  112. A4224 GDC-0152 IAP antagonist,potent amd samll-molecule
  113. A3541 LCL161 Antagonist of IAPs inhibitor
  114. B4653 BV6 Selective inhibitor of IAP proteins
  115. A3220 Bardoxolone Once-a-day treatment for CKD
  116. N2285 Dimethylfraxetin Extracted from Fraxinus chinensis;Store the product in sealed, cool and dry condition.
  117. B1931 Dimethyl Fumarate Dimethyl fumarate is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator. Dimethyl fumarate induces upregulation of antioxidant gene expression.
  118. B3576 Omaveloxolone (RTA-408) Omaveloxolone (RTA-408)
  119. B3577 CDDO-EA
  120. A2005 Nutlin-3b MDM2/p53 inhibitor
  121. A4204 JNJ-26854165 (Serdemetan) Top Seller P53 activator, blocking Mdm2-p53 interaction
  122. B6058 (±)-Nutlin-3 MDM2 antagonist, potent and selective
  123. B4984 MI-773 (SAR405838)
  124. B4813 Pifithrin-β
  125. A9903 p53/MDM2 Set I
  126. A3762 RG7112 MDM2 inhibitor, first clinical
  127. A4202 RITA (NSC 652287) Mdm2-p53 interaction and p53 ubiquitination blocking
  128. A3763 RG7388 MDM2 antagonist, oral, selective
  129. A3693 p53 and MDM2 proteins-interaction-inhibitor chiral P53 and MDM2 proteins-interaction-inhibitor
  130. A3694 p53 and MDM2 proteins-interaction-inhibitor racemic P53 and MDM2 proteins-interaction-inhibitor
  131. B4756 YH239-EE p53-MDM2 antagonist, potent
  132. A4230 NSC 66811 MDM2 inhibitor
  133. A4209 NSC 207895 (XI-006) MDMX inhibitor,anti-cancer agent
  134. A4228 Nutlin-3 Top Seller MDM2 antagonist,inhibits MDM2-p53 interaction
  135. A4206 Pifithrin-α (PFTα) p53 inhibitor
  136. B6045 NSC59984 Restores the p53 signaling pathway
  137. A8724 ONC201 activates p53-independent apoptosis
  138. A8567 Tenovin-3 Top Seller Tenovin-3
  139. A3671 Nutlin-3a chiral Top Seller MDM2 inhibitor, antiproliferative and antiproapoptotic
  140. A4486 SJ 172550 MDMX inhibitor
  141. A4203 Tenovin-1 Top Seller SIRT2 inhibitor, activates p53
  142. A4482 Pifithrin-μ Inhibitor of p53 binding and anti-apoptotic
  143. A4477 Cyclic Pifithrin-α hydrobromide P53 inhibitor
  144. A1094 tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus] P53 binding protein fragment
  145. A1083 p53 tumor suppressor fragment Regulates cell cycle
  146. A4476 CP 31398 dihydrochloride p53 stabilizer
  147. A4208 NSC 319726 Reactivator of mutant p53
  148. A4478 HLI 373 Hdm2 ubiquitin ligase (E3) inhibitor
  149. A8804 AMG232 p53-MDM2 inhibitor, novel
  150. A4479 MIRA-1 Restorer of wild-type p53 conformation/cellular function
  151. A4480 NSC 146109 hydrochloride Antitumor agent,p53-dependent transcription activator
  152. A4481 PhiKan 083 p53 stabilizer
  153. A4485 RETRA hydrochloride Antitumor agent
  154. A4487 WR 1065 P53/p21waf-1/MDM2 activator
  155. B4677 NVP-CGM097
  156. B9013 U 73343
  157. B3422 U-73122 U-73122 is an inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase).
  158. A3343 D609 PC-PLC inhibitor
  159. A3833 SPK-601 Potent PC-PLC inhibitor,antimicrobial agent
  160. B9005 RHC 80267 diacylglycerol lipase inhibitor
  161. A8679 CRT 0066101 PKD inhibitor
  162. A8678 CID 755673 PKD inhibitor
  163. A8223 CID 2011756 Top Seller PKD inhibitor
  164. A3524 kb NB 142-70 Inhibitor of protein kinase D,selective
  165. A3787 Salirasib Inhibitor of active Ras protein
  166. A3947 YM-155 hydrochloride Potent survivin inhibitor
  167. A4390 Pemetrexed Top Seller TS, DHFR,GARFT and AICARFT inhibitor
  168. A8542 Triflurdine (Viroptic) Anti-herpesvirus antiviral drug
  169. B2092 Doxifluridine Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.
  170. B5892 Nolatrexed (AG-337) Non-classical thymidylate synthase inhibitor
  171. A3707 Pemetrexed disodium hemipenta hydrate Antifolate and antimetabolite agent
  172. A4213 Necrostatin-1 RIP1 inhibitor
  173. A4211 Lenalidomide (CC-5013) Top Seller Antineoplastic agent,inhibits angiogenesis
  174. A4212 Pomalidomide (CC-4047) Top Seller Immunomodulator,antumor/anti-angiogenic
  175. A4216 Thalidomide Immunomodulatory agent,sedative drug,angiogenesis inhibitor
  176. A2604 Celastrol Antioxidant, anti-inflammatory and immunosuppressive agent
  177. A3547 Lenalidomide hydrochloride TNF-α secretion inhibitor
  178. A3652 Necrostatin 2 In vitro necroptosis inhibitor
  179. A3960 Necrostatin 2 racemate In vitro necroptosis inhibitor
  180. B1188 Lenalidomide hemihydrate Lenalidomide (Revlimid, CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM.
  181. A3961 Necrostatin 2 S enantiomer In vitro necroptosis inhibitor
  182. B6090 Bioymifi
  183. B3921 Roquinimex
  184. B7790 UC 112 IAP inhibitor
  185. B7731 Necrosulfonamide New Product
  186. A4475 TLQP 21 VGF-derived peptide
  187. A4474 NQDI 1 ASK1, MAP3K5 inhibitor
  188. A4473 Melphalan DNA alkylating agent
  189. A4472 Mdivi 1 Selective DRP1/Dnm1 inhibitor, cell-permeable
  190. A4471 GRI 977143 LPA2 receptor non-lipid agonist
  191. A4469 DAPK Substrate Peptide Synthetic peptide substrate for DAPK
  192. A4468 Cesium chloride Potassium channel blocker
  193. A8738 TASIN-1 inhibitor of mutant adenomatous polyposis coli (APC)

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