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Home >> Signaling Pathways >> Apoptosis


Apoptosis, also known as programed cell death, is a tightly controlled cellular process which is characterized by membrane blebbing, cell shrinkage, chromatin condensation, and DNA fragmentation.

Products for  Apoptosis

Research Area

  1. Cat.No. Product Name Information
  2. B6023 PD-1/PD-L1 inhibitor 2 PD-1/PD-L1 interaction inhibitor
  3. A3523 Kaempferol Apoptosis inducer;antioxidant;flavonoid
  4. A1902 Z-VAD-FMK Cell-permeable, irreversible pan-caspase inhibitor
  5. A9901 Caspase Inhibitor Set I Caspase Inhibitors
  6. A1901 Q-VD-OPh hydrate Top Seller Cell-permeable, irreversible pan-caspase inhibitor
  7. A1925 Caspase-3/7 Inhibitor I Top Seller Caspase-3/7 inhibitor
  8. A8955 Z-YVAD-FMK Caspase-1 inhibitor
  9. A1921 Z-DQMD-FMK Top Seller Caspase-3 inhibitor,cell-permeable
  10. A1922 Z-VDVAD-FMK Top Seller Caspase-2 inhibitor
  11. A1923 Z-VEID-FMK Top Seller Caspase-6 inhibitor
  12. A1920 Z-DEVD-FMK Top Seller Caspase-3 inhibitor
  13. A8238 VX-765 Caspase-1 inhibitor,potent and selective
  14. A8165 Q-VD(OMe)-OPh Top Seller Pan-caspase inhibitor
  15. A8177 PAC-1 Top Seller Procaspase-3 activator
  16. B3233 Z-LEHD-FMK Irreversible Caspase-9 inhibitor.
  17. B3232 Z-IETD-FMK Caspase-8 inhibitor
  18. A1930 Apoptosis Inhibitor Top Seller Associate with caspase-3 inhibition
  19. A1924 Z-WEHD-FMK Caspase 5 inhibitor,potent,cell-permeable and irreversible
  20. A1904 Boc-D-FMK Pan-caspase inhibitor
  21. A4016 Apoptosis Activator 2 Indoledione caspase activator, cell-permeable
  22. A4418 Ac-IEPD-AFC Recognition motif for serine protease granzyme B
  23. A8321 Cisplatin Top Seller Inhibits DNA synthesis,chemotherapy drug
  24. A8170 Z-FA-FMK Top Seller Cysteine proteases inhibitor
  25. A4419 Ac-LEHD-AFC Fluorogenic caspase substrate
  26. A3424 Gambogic Acid Caspase activator and apoptosis inducer
  27. A4416 AZ 10417808 Caspase-3 inhibitor,selective non-peptide
  28. A4417 Ivachtin Caspase-3 inhibitor
  29. A4420 PETCM Caspase-3 activator
  30. B4618 Emricasan potent irreversible pan-caspase inhibitor
  31. A4446 R18 14.3.3 proteins Antagonist
  32. A4234 TW-37 Top Seller Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1
  33. A3327 Costunolide Apoptosis inducer
  34. B4782 Epibrassinolide Potential apoptosis inducer;steroidal plant growth stimulant
  35. C3296 MPI-0441138 inducer of apoptosis and growth inhibition
  36. B7760 CFM 4 Interferes with CARP-1 binding to APC-2
  37. A1984 Bendamustine HCl Cytostatic agent for non-Hodgkin lymphomas
  38. A8244 Cycloheximide Antibiotic,inhibiter of protein synthesis in eukaryotes
  39. A4453 NSC 687852 (b-AP15) 19S regulatory particle Inhibitor
  40. A4452 Mitomycin C Inhibits DNA synthesis,antibiotic and antitumor agent
  41. A3237 Betulinic acid Anti-HIV and antitumor compound,pentacyclic triterpenoid
  42. A3218 BAM7 BAX activator,direct and selective
  43. A4188 2-Methoxyestradiol (2-MeOE2) Apoptotic, antiproliferative and antiangiogenic agent
  44. A8176 Apicidin Potent HDAC inhibitor
  45. N1719 Kaempferol Apoptosis inducer;antioxidant;flavonoid
  46. A3118 3,3'-Diindolylmethane Anticancer and antineoplastic agent
  47. A3265 Brassinolide Plant growth regulator
  48. A3278 Capsaicin TRPV1 receptor agonist
  49. A3335 Curcumin Tyrosinase inhibitor
  50. A3583 Matrine Alkaloid found in Sophora plant
  51. A3746 R1530 Antiangiogenesis,mitosis-angiogenesis inhibitor (MAI)
  52. A3826 SMIP004 Apoptosis inducer
  53. A3886 Trabectedin Antitumour agent
  54. B4760 Raltegravir potassium salt HIV integrase inhibitor
  55. B1228 PM00104 Potent antimyeloma agent
  56. B3255 Meisoindigo Apoptosis inducer;potential agent for AML
  57. A4448 Actinomycin D RNA polymerase inhibitor
  58. A4447 2,3-DCPE hydrochloride Bcl-XL protein expression downregulator
  59. A4449 C 75 Fatty acid synthase (FAS) inhibitor
  60. A4450 CHM 1 Tubulin polymerization inhibitor
  61. A8188 Atractyloside Dipotassium Salt ANT inhibitor
  62. A4451 Deguelin Anticancer and antiviral agent
  63. A4454 Oncrasin 1 Proapoptotic agent
  64. A4457 Streptozocin Antibiotic and antitumor agent
  65. A4455 Piperlongumine Inducer of cell-death
  66. A4456 Plumbagin Anticancer agent
  67. A4484 PRIMA-1MET Top Seller Restore mutant p53 activity, induce BAX and PUMA
  68. A4459 Bax channel blocker Inhibitor of Bax-mediated mitochondrial cytochrome c release
  69. A4483 PRIMA-1 Top Seller BAX inhibitor
  70. A4460 Bax inhibitor peptide P5 Bax inhibitor
  71. A4461 Bax inhibitor peptide V5 Bax inhibitor
  72. A4462 Bax inhibitor peptide, negative control Peptide inhibit Bax translocation to mitochondria
  73. A3935 WEHI-539 Bcl-xL inhibitor,potent and selective
  74. B6094 BH3I-1 Bcl-2 or Bcl-XL inhibitor
  75. A8737 S63845 MCL1 inhibitor
  76. B6011 A-1210477 MCL-1 inhibitor
  77. B5978 BDA-366 Selective antagonist of BCL2 BH4 domain
  78. B5846 Radotinib(IY-5511) Bcr-Abl tyrosine kinase inhibitor
  79. B4902 (+)-Apogossypol inhibitor of Bcl-2 family proteins
  80. A8194 ABT-199 Bcl-2 inhibitor,potent and selective
  81. A8193 ABT-737 Top Seller Bcl-2 inhibitor
  82. A3007 ABT-263 (Navitoclax) Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w
  83. A9902 Bcl Family Set I Bcl family inhibitors
  84. B4901 Pyridoclax Mcl-1 inhibitor
  85. B4881 UMI-77 Mcl-1 inhibitor, novel
  86. A4194 Obatoclax mesylate (GX15-070) Potent Bcl-2 inhibitor
  87. A8168 HA14-1 Top Seller Bcl-2 inhibitor,potent and cell-permeable
  88. B1080 Marinopyrrole A Selective Mcl-1 inhibitor
  89. A4199 Sabutoclax pan-Bcl-2 inhibitor
  90. A4198 BM-1074 Bcl-2/Bcl-xL inhibitor,potent and selective
  91. A4200 Apogossypolone (ApoG2) Bcl-2 inhibitor,nonpeptidic small molecule
  92. A4463 BIM, Biotinylated Bim peptide fragment with a biotin moiety attached
  93. A4464 iMAC2 MAC inhibitor
  94. A4465 MIM1 Mcl-1 Inhibitor
  95. A4466 Muristerone A TRAIL- and hFasL-induced apoptosis inhibitor
  96. N2135 Gossypol PAF inhibitor;anti-fertility and anti-cancer
  97. A3196 AT-101 BH3-mimetic,gossypol enantiomer
  98. B4691 Mcl1-IN-1 Myeloid cell factor 1 inhibitor
  99. A8634 WEHI-539 hydrochloride Bcl-xL inhibitor,high affinity and selective
  100. B6163 A-1155463 BCL-XL inhibitor, potent and selective
  101. B6164 A-1331852 BCL-XL inhibitor, potent and selective
  102. A3847 SU5416 VEGF receptor inhibitor and AHR agonist
  103. A4237 Amuvatinib (MP-470, HPK 56) Top Seller Tyrosine kinase inhibitor
  104. A4116 Danusertib (PHA-739358) Top Seller Pan-aurora kinase inhibitor
  105. A4145 TG101209 Top Seller JAK2/3 inhibitor
  106. C3080 AD57 (hydrochloride) polypharmacological cancer therapeutic that inhibits RET.
  107. A8236 Regorafenib Top Seller Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
  108. A3750 Regorafenib hydrochloride Tyrosine kinase inhibitor
  109. A3751 Regorafenib monohydrate Tyrosine kinase inhibitor
  110. A3891 Triptolide IL-2/MMP-3/MMP7/MMP19 inhibitor
  111. A4219 Birinapant (TL32711) Potent XIAP/cIAP1 antagonist
  112. A4221 YM155 Survivin suppressant,apoptosis inhibitor
  113. A3019 AT-406 (SM-406) IAP inhibitor
  114. A8815 SM-164 Anticancer agent
  115. A8235 Embelin XIAP inhibitor,cell-permeable
  116. A4224 GDC-0152 IAP antagonist,potent amd samll-molecule
  117. A3541 LCL161 Antagonist of IAPs inhibitor
  118. B4653 BV6 Selective inhibitor of IAP proteins
  119. N2285 Dimethylfraxetin Extracted from Fraxinus chinensis;Store the product in sealed, cool and dry condition.
  120. A3220 Bardoxolone Once-a-day treatment for CKD
  121. C3234 2-HBA indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
  122. B1931 Dimethyl Fumarate nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator
  123. B3576 Omaveloxolone (RTA-408) Nrf2 activator
  124. B3577 CDDO-EA activator of Nrf2/ARE
  125. A2005 Nutlin-3b MDM2/p53 inhibitor
  126. A4204 JNJ-26854165 (Serdemetan) Top Seller P53 activator, blocking Mdm2-p53 interaction
  127. A9903 p53/MDM2 Set I For inhibiting MDM2-p53 interaction
  128. B4813 Pifithrin-β potent p53 inhibitor
  129. B4984 MI-773 (SAR405838) orally available MDM2 antagonist
  130. A3762 RG7112 MDM2 inhibitor, first clinical
  131. A4202 RITA (NSC 652287) Mdm2-p53 interaction and p53 ubiquitination blocking
  132. B6058 (±)-Nutlin-3 MDM2 antagonist, potent and selective
  133. A3763 RG7388 MDM2 antagonist, oral, selective
  134. A3693 p53 and MDM2 proteins-interaction-inhibitor chiral P53 and MDM2 proteins-interaction-inhibitor
  135. A3694 p53 and MDM2 proteins-interaction-inhibitor racemic P53 and MDM2 proteins-interaction-inhibitor
  136. B4756 YH239-EE p53-MDM2 antagonist, potent
  137. A4230 NSC 66811 MDM2 inhibitor
  138. A4209 NSC 207895 (XI-006) MDMX inhibitor,anti-cancer agent
  139. A4228 Nutlin-3 Top Seller MDM2 antagonist,inhibits MDM2-p53 interaction
  140. A4206 Pifithrin-α (PFTα) p53 inhibitor
  141. C3192 CBL0137 (hydrochloride) curaxin that activates p53 and inhibits NF-κB
  142. C3171 CBL0137 curaxin that activates p53 and inhibits NF-κB
  143. B6198 ReACp53 inhibit p53 amyloid formation
  144. B6190 NSC348884 nucleophosmin inhibitor
  145. B6045 NSC59984 Restores the p53 signaling pathway
  146. A8724 ONC201 activates p53-independent apoptosis
  147. A8567 Tenovin-3 Top Seller p53 activator
  148. A4486 SJ 172550 MDMX inhibitor
  149. A3671 Nutlin-3a chiral Top Seller MDM2 inhibitor, antiproliferative and antiproapoptotic
  150. A4203 Tenovin-1 Top Seller SIRT2 inhibitor, activates p53
  151. A4482 Pifithrin-μ Inhibitor of p53 binding and anti-apoptotic
  152. A4477 Cyclic Pifithrin-α hydrobromide P53 inhibitor
  153. A1094 tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus] P53 binding protein fragment
  154. A1083 p53 tumor suppressor fragment Regulates cell cycle
  155. A4476 CP 31398 dihydrochloride p53 stabilizer
  156. A4208 NSC 319726 Reactivator of mutant p53
  157. A4478 HLI 373 Hdm2 ubiquitin ligase (E3) inhibitor
  158. A8804 AMG232 p53-MDM2 inhibitor, novel
  159. A4479 MIRA-1 Restorer of wild-type p53 conformation/cellular function
  160. A4480 NSC 146109 hydrochloride Antitumor agent,p53-dependent transcription activator
  161. A4481 PhiKan 083 p53 stabilizer
  162. A4485 RETRA hydrochloride Antitumor agent
  163. A4487 WR 1065 P53/p21waf-1/MDM2 activator
  164. B4677 NVP-CGM097 potent and selective MDM2 inhibitor
  165. B3422 U-73122 inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase)
  166. B9013 U 73343 negative control of U-73122 for PLC inhibition
  167. A3343 D609 PC-PLC inhibitor
  168. A3833 SPK-601 Potent PC-PLC inhibitor,antimicrobial agent
  169. B9005 RHC 80267 diacylglycerol lipase inhibitor
  170. A8679 CRT 0066101 PKD inhibitor
  171. A8678 CID 755673 PKD inhibitor
  172. A8223 CID 2011756 Top Seller PKD inhibitor
  173. A3524 kb NB 142-70 Inhibitor of protein kinase D,selective
  174. A3787 Salirasib Inhibitor of active Ras protein
  175. A3947 YM-155 hydrochloride Potent survivin inhibitor
  176. B2092 Doxifluridine oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU)
  177. A4390 Pemetrexed Top Seller TS, DHFR,GARFT and AICARFT inhibitor
  178. A8542 Triflurdine (Viroptic) Anti-herpesvirus antiviral drug
  179. B5892 Nolatrexed (AG-337) Non-classical thymidylate synthase inhibitor
  180. A3707 Pemetrexed disodium hemipenta hydrate Antifolate and antimetabolite agent
  181. A4211 Lenalidomide (CC-5013) Top Seller Antineoplastic agent,inhibits angiogenesis
  182. A4212 Pomalidomide (CC-4047) Top Seller Immunomodulator,antumor/anti-angiogenic
  183. A4213 Necrostatin-1 RIP1 inhibitor
  184. C3129 R-7050 TNF-α receptor signaling antagonist,cell-permeable
  185. B6109 CPI-1189 necrosis factor (TNF) alpha inhibitor
  186. A4216 Thalidomide Immunomodulatory agent,sedative drug,angiogenesis inhibitor
  187. B6194 GSK481 RIP1(Receptor Interacting Protein Kinase 1) inhibitor
  188. A2604 Celastrol Antioxidant, anti-inflammatory and immunosuppressive agent
  189. A3547 Lenalidomide hydrochloride TNF-α secretion inhibitor
  190. A3652 Necrostatin 2 In vitro necroptosis inhibitor
  191. A3960 Necrostatin 2 racemate In vitro necroptosis inhibitor
  192. B1188 Lenalidomide hemihydrate TNF-α secretion inhibitor
  193. A3961 Necrostatin 2 S enantiomer In vitro necroptosis inhibitor
  194. B6090 Bioymifi death receptor DR5 activator
  195. B3921 Roquinimex quinoline derivative immunostimulant
  196. A4472 Mdivi 1 Selective DRP1/Dnm1 inhibitor, cell-permeable
  197. B7790 UC 112 IAP inhibitor
  198. B7731 Necrosulfonamide Necroptosis inhibitor
  199. A4475 TLQP 21 VGF-derived peptide
  200. A4473 Melphalan DNA alkylating agent
  201. A4471 GRI 977143 LPA2 receptor non-lipid agonist

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