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JWH 133

Catalog No.
B7941
 
Grouped product items
SizePriceStock Qty
5mg (solution)
$171.00
Ship with 5-10 days
10mg (solution)
$277.00
Ship with 5-10 days
25mg (solution)
$608.00
Ship with 5-10 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

JWH 133 is a synthetic cannabinoid (CB) with Ki values of 3.4 nM and 677 nM for the peripheral CB2 receptor and central CB1 receptor, respectively[1]. 

JWH 133 inhibits tumor growth in mice, promoting apoptosis and destroying angiogenesis[2]. JWH 133 also inhibits inflammation of experimental colitis and pancreatitis in mice and in vitro models[3]. 

References:

[1]. Huffman J W, Liddle J, Yu S, et al. 3-(1',1'-Dimethylbutyl)-1-deoxy-Δ8-THC and related compounds: synthesis of selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry, 1999, 7: 2905-2914.

[2]. Casanova M L, Blázquez C, Martínez-Palacio J, et al. Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. Journal of Clinical Investigation, 2003, 111(1): 43-50.

[3]. Kimball E S, Schneider C R, Wallace N H, et al. Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium. American Journal of Physiology and Gastrointestinal Liver Physiology, 2006,  291(2): G364-G371.

Chemical Properties

Physical AppearanceA solution in methyl acetate. To change the solvent, simply evaporate the acetate containing under a gentle stream of nitrogen and immediately add the solvent of choice.
StorageStore at -20°C
M.Wt312.49
Cas No.259869-55-1
FormulaC22H32O
SolubilitySoluble in DMSO
Chemical Name(6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene
SDFDownload SDF
Canonical SMILESCCCC(C)(C1=CC2=C([[email protected]]3[[email protected]@H](CC=C(C3)C)C(C)(O2)C)C=C1)C
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

JWH 133