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EGFR

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

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  1. AZD-9291
    B1104 AZD-9291
     1 Citation
    Target: EGFR
    Summary: Mutated forms EGFR inhibitor
      ≥24.98 mg/mL
  2. FIIN-2
    A8696 FIIN-2
    Target: FGFR
    Summary: Irreversible inhibitor of FGFR
      ≥31.75 mg/mL
  3. Dacomitinib (PF299804, PF299)
    A8319 Dacomitinib (PF299804, PF299)
    Target: ErbB
    Summary: HER inhibitor
      ≥23.5 mg/mL
  4. Neratinib (HKI-272)
    A8322 Neratinib (HKI-272)
     1 Citation
    Target: EGFR
    Summary: HER2/EGFR inhibitor,potent and irreversible
      insoluble in H2O; ≥13.93 mg/mL
  5. PD168393
    A2024 PD168393
    Target: PDGFR|FGFR|EGFR|PKC|insulin
    Summary: EGFR inhibitor

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