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Items 151-160 of 316

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  1. K-Ras(G12C) inhibitor 12
    B4876 K-Ras(G12C) inhibitor 12
    Summary: allosteric inhibitor of K-Ras(G12C)
      ≥8.98 mg/mL
  2. URMC-099
    B4877 URMC-099
    Target: MLK3
    Summary: MLK3 inhibitor, orally bioavailable and brain penetrant
      ≥21.1 mg/mL
  3. Lomitapide
    B4885 Lomitapide
    Summary: MTP inhibitor, orally active
      ≥22.4 mg/mL
  4. CB-839
    B4799 CB-839
     1 Citation
    Target: Glutaminases
    Summary: glutaminase inhibitor
      ≥28.6 mg/mL
  5. ESI-09
    B4814 ESI-09
    Summary: EPAC inhibitor, specific
      ≥33.1 mg/mL
  6. CPI-360
    B4836 CPI-360
    Summary: EZH2 inhibitor
      Soluble in DMSO
  7. BRD4770
    B4837 BRD4770
    Target: Histone Methyltransferase
    Summary: novel G9a(EHMT2) inhibitor
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  8. YL-109
    B4857 YL-109
    Summary: novel anticancer agent
      insoluble in H2O; ≥11.4 mg/mL
  9. Ro 48-8071
    B4859 Ro 48-8071
    Summary: Oxidosqualene cyclase inhibitor
      ≥14.6 mg/mL
  10. Ro 48-8071 fumarate
    B4860 Ro 48-8071 fumarate
    Summary: Oxidosqualene cyclase inhibitor
      Soluble in DMSO

Items 151-160 of 316

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Relate Categories
Specificity
  1. Selective42item
  2. Non-Selective1 item
Reversibility
  1. Irreversible1 item
Target
  1. MMP1 item
  2. Voltage-gated Potassium (KV) Channels1 item
  3. Farnesoid X receptors (FXRs)1 item
  4. P-glycoprotein (P-gp)1 item
  5. Neuraminidases (NA)1 item
  6. RARs1 item
  7. Microtubules/Tubulins1 item
  8. AMPK1 item
  9. eIF4E/eIF3G interaction1 item
  10. Topoisomerases1 item
  11. Cytochrome P450 (CYP450)1 item
  12. Toll-like receptors (TLRs)1 item
  13. BMI-11 item
  14. MLK31 item
  15. Protease-Activated Receptors1 item
  16. Calcium chelator1 item
  17. Dehydrogenase1 item
  18. BCPCF efflux1 item
  19. D1 and D5 Receptors1 item
  20. D2 Receptors1 item
  21. D3 Receptors1 item
  22. Angiotensin-Converting Enzymes (ACEs)1 item
  23. Autophagy1 item
  24. COX1 item
  25. C5a receptors1 item
  26. YAP1 item
  27. eIF4F1 item
  28. Glutaminases2item
  29. Carbonic Anhydrases3item
  30. BLM1 item
  31. NADPH Oxidases1 item
  32. TAK11 item
  33. Histamine H1 Receptors1 item
  34. DYRK1 item
  35. Ionophores1 item
  36. MNK1 item
  37. eEF-21 item
  38. Inward Rectifier Potassium (Kir) Channels1 item
  39. fibrinolysis1 item
  40. D4 Receptors1 item
  41. Aldosterone receptor1 item
  42. Hydroxylases1 item
  43. Antioxidants1 item
  44. ATGL1 item
  45. AChR1 item
  46. calcium uptake1 item
  47. haspin kinase1 item
  48. STK1 item
  49. GABA receptors1 item
  50. Vitamin D receptors (VDRs)1 item
  51. Pregnane X receptor(PXR)1 item
  52. ICAM1 item
  53. sodium chloride cotransporter1 item
  54. DprE1 item
  55. Histone Methyltransferase1 item
Reported Experiments
  1. Animal Experiments55item
  2. Cell Experiments51item
Related Disease
  1. Acute Myeloid Leukemia2item
  2. Bladder Cancer1 item
  3. Brain Injuries Studies1 item
  4. Breast Cancer4item
  5. Cancer17item
  6. Colon Cancer2item
  7. Colorectal Cancer2item
  8. Dyslipidemia1 item
  9. Glioblastoma1 item
  10. Glioma1 item
  11. HIV2item
  12. Inflammatory Diseases4item
  13. Lung Cancer3item
  14. Lymphoma2item
  15. Osteoporosis1 item
  16. Pancreatic Cancer1 item
  17. Schizophrenia1 item
  18. Tuberculosis1 item