IκB/IKK
IKK (IκB kinase) is an enzyme complex that participates in NF-κB signaling pathway. It phosphorylates and inhibits IκB, thus leads to the activation of NF-κB. It is a target for treatment of inflammatory diseases and cancer.
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B1585 SC-514Summary: ATP-competitive IKK-2 inhibitor, orally active -
B1587 IMD 03541 CitationSummary: IKKβ inhibitor -
A3248 BMS345541 hydrochlorideTarget: IKKSummary: IKK inhibitor,highly selective -
A3485 IKK-2 inhibitor VIIISummary: IKK-2 inhibitor,potent and selective -
N1831 LuteolinTarget: AP-1|MMP|15-lipoxygenasesSummary: Antioxidant and free radical scavenger -
N1846 Tanshinone IIATarget: AP-1|MAGLSummary: Antioxidant and anti-inflammatory reagent -
B4655 BMS-345541(free base)Summary: IKK-1/IKK-2 inhibitor,potent and selective