JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

Home
Signaling Pathways

Signaling Pathways

A3306 Chelerythrine Chloride

Target: PKC

Summary: PKC antagonist

insoluble in H2O; ≥19.2 mg/mL
B5965 Tamoxifen
1 Citation

Target: PKC

Summary: TGF-β modulatory and PKC inhibitory effects

≥18.6 mg/mL
B3523 Fasudil

Target: ROCK|PKC|PKG|PKA|Myosin light chain kinases (MLCKs)

Summary: calcium antagonist

Soluble in DMSO
B3709 Midostaurin (PKC412)

Target: PKC|PKA|KDR|Flk1|PPK|c-Syk|CDK1/CyclinB

Summary: PKC inhibitor

≥57.1 mg/mL
B6803 Rottlerin
1 Citation

Target: PKC|Ca2 /calmodulin-dependent protein kinases (CaMKs)|PRAK|MAPKAP-K2

Summary: PKC inhibitor

insoluble in EtOH; insoluble in H2O; ≥23.6 mg/mL
B2191 Dequalinium Chloride

Target: PKC|Calcium-Activated Potassium (KCa) Channels

Summary: anti-tumor agent and PKC inhibitor

insoluble in H2O; insoluble in ETOH; insoluble in DMSO
B1287 Ro 31-8220

Target: PKC

Summary: pan-PKC inhibitor

Soluble in DMSO
A1670 Enzastaurin (LY317615)
2 Citation

Target: PKC

Summary: PKC beta inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
A5072 GSK690693

Target: Akt|PKC|PKG|PKA|Prk

Summary: Pan-AKT inhibitor,ATP-competitive and potent

≥21.25 mg/mL
A2024 PD168393

Target: PDGFR|FGFR|EGFR|PKC|insulin

Summary: EGFR inhibitor