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Signaling Pathways

Signaling Pathways

A8199 PD153035 hydrochloride
1 Citation

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; insoluble in H2O; ≥3.97 mg/mL
A4092 CUDC-101
1 Citation

Target: Histone Deacetylases (HDACs)|EGFR|ErbB

Summary: Multitargeted HDAC inhibitor

≥21.7 mg/mL
A4139 AG-490
3 Citation

Target: EGFR|JAK

Summary: JAK2/EGFR inhibitor

insoluble in H2O; ≥14.7 mg/mL
A4150 WHI-P154

Target: VEGFR|Src|EGFR|JAK

Summary: JAK3 inhibitor

insoluble in H2O; insoluble in EtOH; ≥125.6 mg/mL
A3145 Afatinib dimaleate

Target: EGFR|HER2

Summary: EGFR inhibitor

≥35.9 mg/mL
A3320 CO-1686 (AVL-301)
1 Citation

Target: EGFR

Summary: EGFR inhibitor

≥27.8 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
B5836 AZ5104

Target: EGFR

Summary: EGFR inhibitor

insoluble in H2O; ≥16.95 mg/mL
B5889 EGF816
2 Citation

Target: EGFR

Summary: Novel covalent inhibitor of mutant-selective EGFR

Soluble in DMSO
B1104 AZD-9291
1 Citation

Target: EGFR

Summary: Mutated forms EGFR inhibitor

≥24.98 mg/mL