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Signaling Pathways

Signaling Pathways

A5790 Cidofovir

Target: CMV

Summary: Anti-CMV drug;inhibitor of viral DNA syntheis

insoluble in EtOH; insoluble in DMSO; ≥13.95 mg/mL
A8458 Lamivudine

Target: HBV Proteases

Summary: Nucleoside analog reverse transcriptase inhibitor

≥10.5 mg/mL
B1119 Efavirenz

Target: HIV-1 reverse transcriptase

Summary: Reverse transcriptase inhibitor

insoluble in H2O; ≥15.55 mg/mL
B2011 Praziquantel

Summary: anthelmintic

insoluble in H2O; ≥14.35 mg/mL
B2127 Rifapentine

Target: RNA Polymerases

Summary: antibiotic drug used in the treatment of tuberculosis

≥30.25 mg/mL
B2231 Amitriptyline HCl

Target: Trk Receptors|5-HT2 Receptors|Norepinephrine transporter|5-HT Transporters

Summary: Serotonin /norepinephrine receptor/5-HT4/5-HT2 inhibitor

≥15.69 mg/mL
B1564 Ranitidine

Target: Histamine H2 Receptors

Summary: Histamine H2-receptor antagonist

≥17.54 mg/mL
B3470 Etonogestrel

Target: Progesterone Receptors

Summary: steroidal progestin

insoluble in H2O; ≥15.05 mg/mL
A3012 Ruxolitinib (INCB018424)
4 Citation

Target: JAK

Summary: JAK inhibitor

insoluble in H2O; ≥15.32 mg/mL
A4015 Disulfiram

Target: Aldehyde Dehydrogenases

Summary: Dopamine β-hydroxylase inhibitor

insoluble in H2O; ≥12 mg/mL