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Signaling Pathways

Signaling Pathways

A3020 (R)-Crizotinib
2 Citation

Target: c-MET

Summary: C-MET/ALK inhibitor,potent and ATP-competitve

insoluble in H2O; insoluble in EtOH; ≥7.51 mg/mL
A4015 Disulfiram

Target: Aldehyde Dehydrogenases

Summary: Dopamine β-hydroxylase inhibitor

insoluble in H2O; ≥12 mg/mL
A4224 GDC-0152
2 Citation

Target: Inhibitor of apoptosis proteins (IAP)

Summary: IAP antagonist,potent amd samll-molecule

≥24.95 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
A3541 LCL161
1 Citation

Target: Inhibitor of apoptosis proteins (IAP)

Summary: Antagonist of IAPs inhibitor

≥25.05 mg/mL
A8715 SBI-0206965
2 Citation

Target: ULK1

Summary: ULK1 inhibitor

≥24.47 mg/mL
B5854 Pexidartinib (PLX3397)
3 Citation

Target: FLT3|c-Kit|CSF1R

Summary: CSF-1R inhibitor

insoluble in EtOH; insoluble in H2O; ≥20.9 mg/mL
N2135 Gossypol
2 Citation

Target: Dehydrogenase

Summary: PAF inhibitor;anti-fertility and anti-cancer

≥25.95 mg/mL
B3672 Indirubin

Target: Cyclin-Dependent Kinases|GSK-3

Summary: cyclin-dependent kinases and GSK-3β inhibitor

insoluble in H2O; insoluble in H2O; insoluble in EtOH; ≥13.1 mg/mL
B6962 CMPD-1

Target: Microtubules/Tubulins|MK2

Summary: inhibitor of p38α-mediated MK2a phosphorylation

<34.94 mg/mL