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Signaling Pathways

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  1. Enzastaurin (LY317615)
    A1670 Enzastaurin (LY317615)
     2 Citation
    Target: PKC
    Summary: PKC beta inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
  2. Go 6976
    A8341 Go 6976
    Target: PKC
    Summary: PKCα/PKCβ1 inhibitor
      ≥15.77 mg/mL
  3. Sotrastaurin (AEB071)
    A8525 Sotrastaurin (AEB071)
    Target: PKC
    Summary: PKC inhibitor
      ≥21.9 mg/mL
  4. Tamoxifen
    B5965 Tamoxifen
     1 Citation
    Target: PKC
    Summary: TGF-β modulatory and PKC inhibitory effects
      ≥18.6 mg/mL
  5. H-7 dihydrochloride
    B6342 H-7 dihydrochloride
    Target: PKC|PKG|PKA|Myosin light chain kinases (MLCKs)
    Summary: protein kinase inhibitor
      Soluble in DMSO
  6. Rottlerin
    B6803 Rottlerin
     1 Citation
    Target: PKC|Ca2 /calmodulin-dependent protein kinases (CaMKs)|PRAK|MAPKAP-K2
    Summary: PKC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥23.6 mg/mL

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