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Items 31-40 of 1104

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  1. Pyroxamide
    A4497 Pyroxamide
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1 inhibitor
      Soluble in DMSO
  2. Tubacin
    A4501 Tubacin
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor,potent,selective,reversible,cell-permeable
      insoluble in EtOH; insoluble in H2O; ≥7.19 mg/mL
  3. PX 12
    A4509 PX 12
    Target: Trx
    Summary: Trx-1 inhibitor
      insoluble in H2O; ≥8.75 mg/mL
  4. Cercosporamide
    A4511 Cercosporamide
    Target: JAK|MNK
    Summary: Mnk2 and JAK3 inhibitor
      soluble in DMSO
  5. Cucurbitacin I
    A4512 Cucurbitacin I
    Target: STAT|JAK
    Summary: STAT3/JAK2 signaling inhibitor
      ≥22.45 mg/mL
  6. Fostriecin sodium salt
    A4536 Fostriecin sodium salt
    Target: PP1|PP2A|Topoisomerases|PP4
    Summary: Antitumor antibiotic
      Soluble in H2O
  7. NSC 87877
    A4544 NSC 87877
    Target: PTP
    Summary: Shp2 /shp1 PTP inhibitor
      ≥45.9 mg/mL
  8. TC-A 2317 hydrochloride
    A4489 TC-A 2317 hydrochloride
    Target: Aurora Kinases
    Summary: Aurora kinase A inhibitor,potent and selective
      <39.29 mg/mL
  9. NU 9056
    A4492 NU 9056
    Target: Histone Acetyltransferases (HATs)
    Summary: KAT5 (Tip60) HAT inhibitor
      <10 mg/mL
  10. SBHA
    A4498 SBHA
     1 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1/HDAC3 inhibitor,cell-permeable
      insoluble in EtOH; ≥9 mg/mL

Items 31-40 of 1104

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  1. Proteases69item
  2. Apoptosis58item
  3. Chromatin/Epigenetics102item
  4. Metabolism93item
  5. MAPK Signaling32item
  6. Tyrosine Kinase101item
  7. DNA Damage/DNA Repair79item
  8. PI3K/Akt/mTOR Signaling62item
  9. Microbiology & Virology60item
  10. Cell Cycle/Checkpoint71item
  11. Ubiquitination/ Proteasome29item
  12. JAK/STAT Signaling36item
  13. TGF-β / Smad Signaling32item
  14. Angiogenesis7item
  15. GPCR/G protein92item
  16. Stem Cell29item
  17. Membrane Transporter/Ion Channel66item
  18. Cancer Biology5item
  19. Endocrinology and Hormones33item
  20. Neuroscience95item
  21. Obesity, Appetite Control & Diabetes2item
  22. Other Signal Transduction10item
  23. Others119item
  24. Immunology/Inflammation20item
  25. Cardiovascular8item
  26. Vitamin D Related6item
  27. NF-κB1 item
Specificity
  1. Selective635item
  2. Non-Selective5item
Reversibility
  1. Reversible37item
  2. Irreversible28item
Target
  1. Caspases7item
  2. Cyclin-Dependent Kinases21item
  3. Adenosine A2A Receptors3item
  4. Proteasome11item
  5. Cathepsins5item
  6. Histone Deacetylases (HDACs)26item
  7. Inhibitor of apoptosis proteins (IAP)1 item
  8. Akt11item
  9. Bcl-28item
  10. PI3K28item
  11. CXCR4item
  12. Raf10item
  13. Aurora Kinases18item
  14. Bcl-xl3item
  15. CSF-1R4item
  16. Glycoproteins1 item
  17. p971 item
  18. Gap Junctions3item
  19. MDM22item
  20. EZH23item
  21. mTOR16item
  22. Bromodomains5item
  23. AP-13item
  24. MMP7item
  25. Thymidine Phosphorylases1 item
  26. Androgen Receptors3item
  27. Peptidylprolyl isomerases1 item
  28. Acyl coenzyme A: cholesterol acyltransferases1 item
  29. Myosin II ATPases1 item
  30. DT-diaphorases1 item
  31. Voltage-gated Potassium (KV) Channels4item
  32. MER1 item
  33. FLT316item
  34. GSK-36item
  35. Factor Xa4item
  36. Farnesoid X receptors (FXRs)3item
  37. LPA Receptors3item
  38. P-glycoprotein (P-gp)3item
  39. PLK9item
  40. Chk4item
  41. Eph Receptors2item
  42. VEGFR29item
  43. PDGFR19item
  44. c-Kit9item
  45. RET2item
  46. IRAK2item
  47. Bromodomain-containing proteins(BRDs)1 item
  48. Phosphodiesterases (PDEs)13item
  49. Mcl-15item
  50. Hydrolase1 item
  51. Thymidylate Synthase3item
  52. p387item
  53. PKB1 item
  54. JNK2item
  55. Bcr-Abl10item
  56. MEK8item
  57. PORCN1 item
  58. DOT1L1 item
  59. FGFR10item
  60. Nrf21 item
  61. Pim3item
  62. GABAB Receptors1 item
  63. Liver X receptors (LXRs)3item
  64. Sir2-like Family Deacetylases (Sirtuins)3item
  65. Voltage-gated Sodium (NaV) Channels9item
  66. Deubiquitinating enzymes (DUBs)2item
  67. PP11 item
  68. PP2A1 item
  69. Smoothened2item
  70. Neuraminidases (NA)1 item
  71. MET5item
  72. Src15item
  73. RARs8item
  74. Trk Receptors5item
  75. Aminopeptidases2item
  76. NMDA Receptors3item
  77. STAT6item
  78. Microtubules/Tubulins1 item
  79. Estrogen and Related Receptors7item
  80. EGFR18item
  81. Reverse Transcriptases5item
  82. ROCK7item
  83. Hypoxia Inducible Factors (HIFs)1 item
  84. FAK3item
  85. JAK17item
  86. Stearoyl-CoA 9-desaturase (SCD-1)1 item
  87. Syk4item
  88. Progesterone Receptors4item
  89. EZH11 item
  90. DNA-PK6item
  91. HSP908item
  92. AMPK3item
  93. CCR1 item
  94. Angiotensin AT2 Receptors1 item
  95. CFTR2item
  96. Topoisomerases13item
  97. Cytochrome P450 (CYP450)10item
  98. M3 Receptors1 item
  99. Ksp1 item
  100. Renin1 item
  101. ErbB4item
  102. Toll-like receptors (TLRs)4item
  103. Actin2item
  104. Serine Proteases1 item
  105. DNA Methyltransferases3item
  106. ERK6item
  107. HMG-CoA Reductases4item
  108. c-MET6item
  109. PKC12item
  110. Calpains3item
  111. M1 Receptors2item
  112. Ca2 /calmodulin-dependent protein kinases (CaMKs)5item
  113. Protease-Activated Receptors1 item
  114. Lyn1 item
  115. RAD511 item
  116. HER21 item
  117. Pyk22item
  118. 5-HT2 Receptors9item
  119. LRRK25item
  120. S1P receptors2item
  121. Voltage-gated Calcium Channels (CaV)10item
  122. DGAT1 item
  123. Insulin and Insulin-like Receptors4item
  124. PARP6item
  125. CB1 Receptors2item
  126. Pyruvate dehydrogenases (PDH)1 item
  127. ALK6item
  128. Sphingosine kinases (SphKs)2item
  129. Monocarboxylate transporters (MCTs)1 item
  130. CETP1 item
  131. Dehydrogenase1 item
  132. PKG2item
  133. PKA5item
  134. Myosin light chain kinases (MLCKs)2item
  135. GPR301 item
  136. D1 and D5 Receptors3item
  137. D2 Receptors6item
  138. D3 Receptors4item
  139. 5-HT1 Receptors8item
  140. 5-HT7 Receptors2item
  141. Lactate Dehydrogenases (LDH)2item
  142. MK22item
  143. 5-HT3 Receptors6item
  144. Angiotensin-Converting Enzymes (ACEs)3item
  145. Tie-23item
  146. RSK2item
  147. Free Fatty Acid Receptors1 item
  148. phosphatases1 item
  149. Autophagy4item
  150. ATM/ATR5item
  151. COX13item
  152. YAP1 item
  153. CK11 item
  154. Histamine H4 Receptors2item
  155. Farnesyl Diphosphate Synthases1 item
  156. CK24item
  157. HIPK21 item
  158. HIPK31 item
  159. HIV Integrases1 item
  160. Squalene epoxidases3item
  161. PRAK1 item
  162. MAPKAP-K21 item
  163. Melatonin Receptors1 item
  164. 20S proteasomal chymotrypsin1 item
  165. Geranylgeranyltransferase I1 item
  166. Farnesyltransferase1 item
  167. Nampt3item
  168. eIF4F1 item
  169. Cdc421 item
  170. SRPK11 item
  171. P2X Receptors3item
  172. Glutaminases2item
  173. Carbonic Anhydrases7item
  174. Ron1 item
  175. G9a1 item
  176. BLM1 item
  177. HSV2item
  178. Adenosine A2B Receptors1 item
  179. NADPH Oxidases3item
  180. Glutamate (Metabotropic) Group I Receptors3item
  181. Calcium-activated chloride channels (CaCC)1 item
  182. GPR351 item
  183. Aldehyde Dehydrogenases2item
  184. Synthases/Synthetases3item
  185. MAGL1 item
  186. NPY Receptors2item
  187. Leukotriene and Related Receptors2item
  188. Histamine H1 Receptors12item
  189. RAR/RXR2item
  190. Sigma Receptors2item
  191. Na /K ATPases2item
  192. P1101 item
  193. Hck2item
  194. Inositol-requiring enzyme 1 (IRE1)1 item
  195. Na /K /Cl- Symporters (NKCCs)2item
  196. GABAA Receptors3item
  197. Histamine H2 Receptors1 item
  198. Phospholipases1 item
  199. TRP Channel3item
  200. RNA Polymerases3item
  201. DYRK1 item
  202. Norepinephrine transporter1 item
  203. 5-HT Transporters3item
  204. Ionophores2item
  205. Xanthine oxidoreductases1 item
  206. Dihydroorotate dehydrogenase1 item
  207. Guanylyl Cyclases1 item
  208. FoxM11 item
  209. Histone Demethylases1 item
  210. M2 Receptors2item
  211. MNK2item
  212. 5-Lipoxygenases1 item
  213. NO Donors / Precursors1 item
  214. CB2 Receptors1 item
  215. Glucocorticoid Receptors5item
  216. HIV-1 reverse transcriptase1 item
  217. IL Receptors2item
  218. CCL21 item
  219. Norepinephrine transporters1 item
  220. 15-lipoxygenases1 item
  221. Calcium-Activated Potassium (KCa) Channels3item
  222. 5-HT4 Receptors1 item
  223. AChE3item
  224. Insulin Receptors2item
  225. IRG-1R1 item
  226. cAMP1 item
  227. Sulfonylurea receptors1 item
  228. eEF-21 item
  229. Inward Rectifier Potassium (Kir) Channels5item
  230. Peptidoglycan synthesis1 item
  231. CRTH21 item
  232. Cdc71 item
  233. calcium chelator1 item
  234. Nuclear Receptors1 item
  235. CMV2item
  236. ZAP-701 item
  237. Catechol O-Methyltransferase (COMT)2item
  238. fibrinolysis1 item
  239. Angiotensin AT1 Receptors4item
  240. D4 Receptors3item
  241. O6-methylguanine-DNA-methyl-transferase (MGMT)1 item
  242. NMDA receptor1 item
  243. Aldosterone receptor1 item
  244. HBV Proteases1 item
  245. M4 Receptors1 item
  246. M5 Receptors1 item
  247. Hydroxylases2item
  248. Flk-11 item
  249. Adenine receptors1 item
  250. Antioxidants1 item
  251. Papains1 item
  252. RNA synthesis1 item
  253. Protein Arginine Methyltransferases1 item
  254. IMPDH1 item
  255. Na /Ca2 Exchangers (NCXs)1 item
  256. NAE2item
  257. Ubiquitin-activating Enzyme E12item
  258. SUMOylation1 item
  259. ATGL1 item
  260. BACE3item
  261. Cytidine deaminases1 item
  262. GPR401 item
  263. Adenylyl Cyclases1 item
  264. angiogenesis1 item
  265. Glucagon Receptors1 item
  266. 15-PGDH1 item
  267. DPP-45item
  268. DREADD Ligands1 item
  269. PP41 item
  270. c-RET3item
  271. Nonstructural protein 5B (NS5B)1 item
  272. guanylyl cyclase2item
  273. ETA Receptors2item
  274. ETB Receptors1 item
  275. p70 rsk3item
  276. voltage-gated chloride channels1 item
  277. FPTase2item
  278. AChR8item
  279. Retinoic acid-related Orphan Receptors (RORs)1 item
  280. dopamine receptor1 item
  281. 5-HT1 Receptor3item
  282. 5-HT2 Receptor2item
  283. Microtubule/Tubulin3item
  284. Myosin1 item
  285. VEGFR3/FLT41 item
  286. NTRK1/TRKA1 item
  287. CSF-1R/c-Fms1 item
  288. interleukin receptor2item
  289. Menin-MLL2item
  290. Tryptophan hydroxylases (TPH)2item
  291. ADAMs1 item
  292. NMPRTase1 item
  293. Bfl-11 item
  294. TAM kinase1 item
  295. sodium channels1 item
  296. p53-MDM2 interaction2item
  297. nuclear export1 item
  298. CRM11 item
  299. PTP1 item
  300. endothelin receptor1 item
  301. KDR2item
  302. calcium uptake1 item
  303. Fyn kinase1 item
  304. Abl kinases1 item
  305. PARs1 item
  306. AXL1 item
  307. Glyoxalase I1 item
  308. dCTP Pyrophosphatases1 item
  309. Protein polybromo-11 item
  310. SMARCA41 item
  311. SMARCA21 item
  312. Dipeptidyl-peptidase II1 item
  313. p538item
  314. metalloprotease1 item
  315. adrenoceptor2item
  316. HDAC2item
  317. Antifungal2item
  318. KDM2item
  319. 5-HT6 Receptor1 item
  320. LOX1 item
  321. Adenylyl cyclase1 item
  322. Quinone reductase1 item
  323. 5-HT receptors1 item
  324. sodium channel3item
  325. c-Fms tyrosine kinase1 item
  326. PAR2item
  327. human lyase1 item
  328. insulin1 item
  329. Ub-conjugating enzyme (E2) complex1 item
  330. Smoothened receptor1 item
  331. quinone oxidoreductase1 item
  332. cysteine protease2item
  333. Nrf2/ARE signal1 item
  334. PPAR7item
  335. STK1 item
  336. HDM2 ubiquitin ligase1 item
  337. USP1/USF1 complex1 item
  338. IKK1 item
  339. GABA receptors1 item
  340. MSK1 item
  341. prostaglandin FP receptor1 item
  342. gp120-CD4 interaction1 item
  343. TRPV1 item
  344. HCV polymerase3item
  345. Lyn kinase1 item
  346. Ftase1 item
  347. Subtilisin/Kex2p-like proprotein convertase1 item
  348. PC-PLC2item
  349. Elastases1 item
  350. GK1 item
  351. P97 ATPase1 item
  352. ATP synthase1 item
  353. NTPDases1 item
  354. Vitamin D receptors (VDRs)5item
  355. Antibiotic6item
  356. Mer tyrosine kinase1 item
  357. Hec11 item
  358. Calmodulins1 item
  359. cannabinoid receptor1 item
  360. EAA receptor1 item
  361. neprilysin1 item
  362. Calcium-Sensing Receptors (CaSRs)2item
  363. DNA Alkylating2item
  364. GLI1 item
  365. Stem Cell Differentiation1 item
  366. PP2A/Nkd interaction1 item
  367. Rev-Erb Receptors1 item
  368. HMGCR1 item
  369. AAT1 item
  370. ErbB-21 item
  371. adrenergic receptor5item
  372. HIV1 item
  373. 5-HT4 Receptor1 item
  374. PAR receptor1 item
  375. TRPA1 item
  376. sterol demethylase1 item
  377. PDK-11 item
  378. GAPDH1 item
  379. telomerase1 item
  380. Prostanoid Receptors1 item
  381. Histone Acetyltransferases (HATs)3item
  382. Telomerases1 item
  383. Retinoid X receptors (RXR)1 item
  384. complex I of the mitochondrial electron transport chain1 item
  385. constitutive androstane receptor (CAR)1 item
  386. F1 Fo-ATPase1 item
  387. NPFF receptor1 item
  388. Prk1 item
  389. potassium channel1 item
  390. calcium channel1 item
  391. Ribonucleotide Reductases1 item
  392. Trx1 item
  393. Tyrosinases1 item
  394. Neurokinin receptor1 item
  395. HSP701 item
  396. Pregnane X receptor(PXR)1 item
  397. ICAM1 item
  398. ITK1 item
  399. HIF-PH1 item
  400. NOD11 item
  401. NUAK1 item
  402. Rho1 item
  403. Aryl hydrocarbon receptors (AHRs)1 item
  404. Ubiquitin E3 Ligases1 item
  405. DCLK21 item
  406. FAAH1 item
  407. PTK2item
  408. integrase1 item
  409. L3MBTL1 item
  410. phosphatidylinositol kinase1 item
  411. NOS2item
  412. MDMX1 item
  413. TYK22item
  414. MUSK1 item
  415. MAP3K1 item
  416. GPR31 item
  417. AMPA Receptors1 item
  418. Lck1 item
  419. Adenosine Deaminases2item
  420. mitochondrial pyruvate carrier (MPC)1 item
  421. DNA gyrase1 item
  422. sodium chloride cotransporter1 item
  423. SERT1 item
  424. Thrombin Receptor1 item
  425. prolactin secretion1 item
  426. gonadotropin release1 item
  427. DprE1 item
  428. Vitamin D1 item
  429. carnitine reabsorption1 item
  430. Histamine receptors1 item
  431. GluR1 item
  432. 5-HT receptor2item
  433. dopamine receptors1 item
  434. AMPA receptor1 item
  435. 5-alpha Reductases1 item
  436. Flk12item
  437. SAPK1 item
  438. p211 item
  439. DNA Ligases1 item
  440. NOP Receptors1 item
  441. Prostaglandin synthesis1 item
  442. Protein Tyrosine Phosphatases1 item
  443. alkaline phosphatases1 item
  444. ATPases1 item
  445. Transferases1 item
  446. benzodiazepine receptor1 item
  447. Dopamine receptor1 item
  448. Histamine receptor1 item
  449. glutamate release1 item
  450. PAFR1 item
  451. Aromatases2item
  452. DHFR1 item
  453. GARFT1 item
  454. 5-HT1 item
  455. PHF1 item
  456. FGR1 item
  457. YES2item
  458. Fyn2item
  459. ARG1 item
  460. Autotaxin1 item
  461. UCH1 item
  462. RHA1 item
  463. HCV NS3-4A protease1 item
  464. TRPC channel1 item
  465. PKD1 item
  466. Octamer-binding transcription factor 4 (Oct4)1 item
  467. Thioredoxin Reductases1 item
  468. P2Y Receptors1 item
  469. enoyl-acyl-carrier protein reductase1 item
  470. SHIP1 item
  471. FKBP1 item
  472. MCL11 item
  473. Bcl-w1 item
  474. glutathione peroxidase 41 item
  475. NADH oxidase1 item
  476. GLP-2 receptor1 item
  477. S-adenosylhomocysteine hydrolase1 item
  478. Rho-kinase1 item
  479. tropomyosin receptor kinase1 item
  480. LSD1 item
  481. DDX31 item
  482. LPA1 item
  483. PRMT1 item
  484. ACE1 item
  485. GLP1 item
  486. SK1 item
  487. MST1 item
  488. PPK1 item
  489. c-Syk1 item
  490. CDK1/CyclinB1 item
  491. NHE1 item
  492. IDO1 item
  493. Tph1 item
  494. FXR1 item
  495. Cx431 item
  496. PIM1 kinase1 item
  497. phospholipase A21 item
  498. reverse transcriptase1 item
  499. GABAA receptor1 item
  500. epoxide hydrolase1 item
  501. ghrelin receptor1 item
  502. Serotonin (5-HT) reuptake1 item
  503. Cholesterol absorption1 item
  504. Vascular Disrupting Agents (VDA)1 item
  505. Androgen Receptor1 item
  506. Substance P/NK1 Receptor1 item
  507. gp120/CD41 item
  508. ATM1 item
  509. Sirtuin1 item
  510. NE1 item
  511. CRF1 Receptors1 item
  512. PIKfyve1 item
  513. Bax1 item
  514. Glycogen Phosphorylases1 item
  515. MTH11 item
  516. PTEN1 item
  517. Insulin Receptor1 item
  518. NS3/4a Proteases1 item
  519. p90 S6K1 item
Related Disease
  1. Acne2item
  2. Acute Kidney Injury2item
  3. Acute Lung Injury1 item
  4. Acute Myelogenous Leukemia4item
  5. Acute Myeloid Leukemia20item
  6. Acute Renal Failure1 item
  7. Adrenocortical Carcinoma3item
  8. Anesthesia2item
  9. Bacterial Infectios1 item
  10. Biliary Cancer1 item
  11. Bladder Cancer10item
  12. Bladder Carcinoma3item
  13. Bladder Diseases2item
  14. B-lymphoid Malignancies1 item
  15. Brain Injuries Studies3item
  16. Breast Cancer84item
  17. Cancer394item
  18. Castration-resistant Prostate Cancer1 item
  19. Cervical Cancer5item
  20. Cholangiocarcinoma1 item
  21. Chronic Lymphocytic Leukemia6item
  22. Chronic Myeloproliferative Disorders1 item
  23. Clear Cell Renal Cell Carcinoma1 item
  24. Cocaine Abuse1 item
  25. Cocaine-Related Disorders2item
  26. Colon Cancer22item
  27. Colon Carcinoma3item
  28. Colorectal Cancer31item
  29. Depression2item
  30. Diabetes10item
  31. Diffuse Large B-cell Lymphoma1 item
  32. Dyskinesia1 item
  33. Dyslipidemia2item
  34. Epilepsy6item
  35. Erectile Dysfunction3item
  36. Friedreich's Ataxia1 item
  37. Fungi1 item
  38. Glioblastoma19item
  39. Glioma12item
  40. HCV3item
  41. Heart Failure6item
  42. Hepatitis C3item
  43. Hepatocellular Carcinoma5item
  44. HIV12item
  45. HIV Infections13item
  46. Hypercholesterolemia1 item
  47. Inflammation1 item
  48. Inflammatory Diseases9item
  49. Influenza1 item
  50. Kidney Injury Studies3item
  51. Leukemia21item
  52. Liver Cancer3item
  53. Lung Cancer23item
  54. Lung Carcinoma2item
  55. Lymphoma28item
  56. Mantle Cell Lymphoma2item
  57. Melanoma22item
  58. Mixed Lineage Leukemia1 item
  59. Multidrug Resistance Studies1 item
  60. Multiple Myeloma19item
  61. Myelofibrosis2item
  62. Myeloma3item
  63. Narcolepsy1 item
  64. Neuroblastoma8item
  65. Neurocognitive Disorders1 item
  66. Neuronal Protection1 item
  67. Non-small Cell Lung Cancer16item
  68. Non-small Cell Lung Carcinoma1 item
  69. Obsessive-Compulsive Disorder1 item
  70. Osteoporosis2item
  71. Ovarian Cancer24item
  72. Pain Relief1 item
  73. Pancreatic Cancer32item
  74. Pancreatic Carcinoma1 item
  75. Pentacyclic Triterpenoid1 item
  76. Prostate Cancer39item
  77. Psoriasis5item
  78. Psoriasis Vulgaris1 item
  79. Pulmonary Fibrosis2item
  80. Renal Cancer4item
  81. Renal Cell Carcinoma7item
  82. Rheumatoid Arthritis11item
  83. Sarcoma1 item
  84. Schizophrenia7item
  85. Sleep Disorders2item
  86. Soft Tissue Sarcoma1 item
  87. Squamous Cell Carcinoma3item
  88. Thyroid Cancer4item
  89. Transplantation1 item
  90. Tuberculosis4item
  91. Type 2 Diabetes15item