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Signaling Pathways

Signaling Pathways

A4124 TAK-901

Target: Aurora Kinases|FLT3|Src|JAK|LRRK2|Hck|FGR|YES|Fyn|ARG

Summary: Novel Aurora A/B inhibitor

≥25.25 mg/mL
A3741 Pyridone 6

Target: JAK

Summary: Pan-JAK inhibitor

insoluble in H2O; ≥15.45 mg/mL
A3937 XL019

Target: JAK

Summary: JAK2 inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥11.125 mg/mL
A4511 Cercosporamide

Target: JAK|MNK

Summary: Mnk2 and JAK3 inhibitor

soluble in DMSO
A4512 Cucurbitacin I

Target: STAT|JAK

Summary: STAT3/JAK2 signaling inhibitor

≥22.45 mg/mL
A8215 PP 1

Target: Src|EGFR|JAK|ZAP-70

Summary: Src family tyrosine kinase inhibitor
B8023 Cerdulatinib (PRT062070)

Target: JAK|Syk|TYK2

Summary: Syk/JAK inhibitor

≥22.3 mg/mL