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Signaling Pathways

Signaling Pathways

A4015 Disulfiram

Target: Aldehyde Dehydrogenases

Summary: Dopamine β-hydroxylase inhibitor

insoluble in H2O; ≥12 mg/mL
A4064 NVP-BEP800

Target: HSP90

Summary: Oral Hsp90β inhibitor, novel, fully synthetic
A4330 Isotretinoin

Target: RARs

Summary: Dopamine β-hydroxylase activator

insoluble in H2O; ≥13.8 mg/mL
A4381 FK866 (APO866)
1 Citation

Target: Nampt

Summary: NAMPT inhibitor, non-competitive, highly specific

insoluble in H2O; ≥19.6 mg/mL
A4386 Elesclomol (STA-4783)
3 Citation

Summary: Oxidative stress/apoptosis inducer,potent and novel

insoluble in H2O; ≥20.15 mg/mL
A4388 XL-888
1 Citation

Target: HSP90

Summary: Hsp90 inhibitor

insoluble in H2O; insoluble in EtOH; ≥18.2 mg/mL
B4900 Indoximod (NLG-8189)

Summary: Indoleamine 2,3-dioxygenase (IDO) pathway inhibitor

insoluble in DMSO; insoluble in EtOH; ≥1.12 mg/mL
A2213 17-DMAG (Alvespimycin) HCl
1 Citation

Target: HSP90

Summary: Hsp90 inhibitor

≥26.2 mg/mL