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Signaling Pathways

Signaling Pathways

A4111 VX-680 (MK-0457,Tozasertib)

Target: Aurora Kinases

Summary: Aurora kinase inhibitor

≥23.25 mg/mL
A4112 Barasertib (AZD1152-HQPA)
3 Citation

Target: Aurora Kinases

Summary: Aurora Kinase B inhibitor, Potent and selective

≥25.4 mg/mL
A4113 ZM 447439

Target: Aurora Kinases|MEK|Src|Lck

Summary: Aurora Kinase inhibitor,potent and selective

≥25.7 mg/mL
A4114 MLN8054

Target: Aurora Kinases

Summary: Aurora A inhibitor

insoluble in EtOH; insoluble in H2O; ≥39.05 mg/mL
A4115 JNJ-7706621
1 Citation

Target: Cyclin-Dependent Kinases|Aurora Kinases

Summary: Potent CDK/Aurora kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.7 mg/mL
A4118 Hesperadin
1 Citation

Target: Aurora Kinases

Summary: Aurora B kinase inhibitor

≥25.85 mg/mL
A4126 Aurora A Inhibitor I

Target: Aurora Kinases

Summary: Aurora A inhibitor

≥29.4 mg/mL
A4127 GSK1070916

Target: Aurora Kinases

Summary: Aurora B/C inhibitor

≥25.4 mg/mL
A4128 PF-03814735

Target: Aurora Kinases

Summary: Aurora A/B inhibitor

Soluble in DMSO
A3214 AZD1152
1 Citation

Target: Aurora Kinases

Summary: Aurora B kinase inhibitor,highly potent and selective

insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL