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Signaling Pathways

Signaling Pathways

A3958 Veliparib dihydrochloride

Target: PARP

Summary: PARP-1/PARP-2 inhibitor

≥31.7 mg/mL
A3962 AZD1208

Target: Pim

Summary: PIM kinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥18.95 mg/mL
A4496 NSC 3852

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in EtOH; insoluble in H2O; ≥7.35 mg/mL
A4509 PX 12

Target: Trx

Summary: Trx-1 inhibitor

insoluble in H2O; ≥8.75 mg/mL
A4511 Cercosporamide

Target: JAK|MNK

Summary: Mnk2 and JAK3 inhibitor

soluble in DMSO
A4512 Cucurbitacin I

Target: STAT|JAK

Summary: STAT3/JAK2 signaling inhibitor

≥22.45 mg/mL
A4536 Fostriecin sodium salt

Target: PP1|PP2A|Topoisomerases|PP4

Summary: Antitumor antibiotic

Soluble in H2O
A4489 TC-A 2317 hydrochloride

Target: Aurora Kinases

Summary: Aurora kinase A inhibitor,potent and selective

<39.29 mg/mL
A8221 EPZ-6438
5 Citation

Summary: EZH2 inhibitor, potent and selective

≥28.64 mg/mL
A8547 Tubastatin A HCl
1 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC6 inhibitor,potent and selective

insoluble in EtOH; ≥12.34 mg/mL