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Signaling Pathways

Signaling Pathways

B5421 (Z)-4-Hydroxytamoxifen

Target: Estrogen and Related Receptors

Summary: ER modulator, potent and selective

≥38.8 mg/mL
B5455 G-1
4 Citation

Target: GPR30

Summary: GPR30 agonist, potent and selective

≥41.2 mg/mL
B5469 G-15
3 Citation

Target: GPR30

Summary: GPER receptor antagonist

insoluble in H2O; insoluble in EtOH; ≥37 mg/mL
B3470 Etonogestrel

Target: Progesterone Receptors

Summary: steroidal progestin

insoluble in H2O; ≥15.05 mg/mL
B1519 Bazedoxifene HCl

Target: Estrogen and Related Receptors

Summary: Novel, non-steroidal, indole-based estrogen receptor modulator (SERM)

≥25.35 mg/mL
B1518 Erteberel (LY500307)

Target: Estrogen and Related Receptors

Summary: ERβ agonist, potent and selective

insoluble in H2O; ≥14.1 mg/mL
B1510 Medroxyprogesterone acetate

Target: Progesterone Receptors

Summary: Steroidal progestin
B3238 XCT790

Target: Estrogen and Related Receptors

Summary: ERRα agonist

insoluble in H2O; ≥14.9 mg/mL
B1515 Raloxifene HCl

Target: Estrogen and Related Receptors

Summary: Estrogen receptor (ER)

≥22.35 mg/mL