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Signaling Pathways

Items 21-30 of 659

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  1. VX-809
    A8351 VX-809
    Target: CFTR
    Summary: CFTR corrector
      ≥22.6 mg/mL
  2. Furosemide
    A8435 Furosemide
    Target: Na /K /Cl- Symporters (NKCCs)|GABAA Receptors
    Summary: GABAA receptors antagonist
  3. Gabapentin
    A8436 Gabapentin
    Summary: GABA enhancer
  4. Glipizide
    A8438 Glipizide
    Summary: Oral anti-diabetic medication
      insoluble in H2O; ≥16.8 mg/mL
  5. Isradipine (Dynacirc)
    A8453 Isradipine (Dynacirc)
    Summary: Calcium channel blocker
      ≥12.55 mg/mL
  6. Nilvadipine
    A8455 Nilvadipine
    Summary: Calcium channel inhibitor
      insoluble in H2O; ≥12.4 mg/mL
  7. Riluzole
    A8513 Riluzole
    Target: Voltage-gated Sodium (NaV) Channels|glutamate release
    Summary: Sodium channel protein inhibitor
      ≥23.4 mg/mL
  8. SB705498
    A8519 SB705498
    Summary: TRPV1 antagonist,potent and selective
      insoluble in H2O; ≥14.5 mg/mL
  9. Sodium Orthovanadate
    A8524 Sodium Orthovanadate
    Target: Protein Tyrosine Phosphatases|alkaline phosphatases|ATPases
    Summary: PTP inhibitor
      insoluble in DMSO; insoluble in EtOH; ≥6.7 mg/mL
  10. Strontium Ranelate
    A8526 Strontium Ranelate
    Summary: Calcium Channel activator
      insoluble in EtOH; insoluble in DMSO; ≥2.57 mg/mL

Items 21-30 of 659

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Category
  1. AMPAR43item
  2. ATPase38item
  3. Calcium Channel78item
  4. Cannabinoid Transporters6item
  5. CFTR10item
  6. Chloride Channels13item
  7. GABA Receptor89item
  8. Glucose Transporters2item
  9. Glutamate (EAAT) Transporters17item
  10. Glycine Receptors2item
  11. GlyT15item
  12. GTPase6item
  13. Kv1.31 item
  14. ICB1 item
  15. MCT22item
  16. Monoamine transporter1 item
  17. Monocarboxylate Transporters1 item
  18. Multidrug Transporters4item
  19. Na+/Ca2+ Exchanger7item
  20. NKCC3item
  21. NMDA Receptor72item
  22. Nucleoside Transporters3item
  23. Pannexin-12item
  24. P2X purinergic receptor29item
  25. P-gp9item
  26. Proton Pump11item
  27. Potassium Channel76item
  28. Sodium Channel44item
  29. TRP Channel41item
  30. TRPV110item
  31. URAT11 item
  32. Other Channel Modulators8item
  33. MCT3item
  34. Kainate Receptors12item
  35. Ionophore3item
  36. sodium-hydrogen exchanger3item
  37. nAChR1 item
  38. iGluR2item
  39. Chloride Channel1 item
Specificity
  1. Selective57item
Reversibility
  1. Reversible5item
Target
  1. Gap Junctions1 item
  2. Myosin II ATPases1 item
  3. Voltage-gated Potassium (KV) Channels2item
  4. P-glycoprotein (P-gp)4item
  5. GABAB Receptors2item
  6. Voltage-gated Sodium (NaV) Channels10item
  7. NMDA Receptors4item
  8. CFTR4item
  9. Cytochrome P450 (CYP450)2item
  10. DNA Methyltransferases1 item
  11. Epac1 item
  12. Ca2 /calmodulin-dependent protein kinases (CaMKs)2item
  13. Calcium ionophores1 item
  14. Voltage-gated Calcium Channels (CaV)10item
  15. GTPases1 item
  16. Monocarboxylate transporters (MCTs)2item
  17. Myosin light chain kinases (MLCKs)1 item
  18. CaM-KK1 item
  19. AMPA1 item
  20. Na /H Exchangers (NHEs)1 item
  21. Delayed rectifier outward potassium current (IKr)1 item
  22. P2X Receptors1 item
  23. Carbonic Anhydrases1 item
  24. Calcium-activated chloride channels (CaCC)1 item
  25. GPR351 item
  26. Urokinases1 item
  27. Synthases/Synthetases1 item
  28. Na /K ATPases2item
  29. Na /K /Cl- Symporters (NKCCs)2item
  30. GABAA Receptors3item
  31. TRP Channel2item
  32. Ionophores1 item
  33. Calcium-Activated Potassium (KCa) Channels2item
  34. Proton Pump1 item
  35. cAMP1 item
  36. Sulfonylurea receptors1 item
  37. Inward Rectifier Potassium (Kir) Channels3item
  38. Na /Ca2 Exchangers (NCXs)1 item
  39. Myosin1 item
  40. 5-HT receptors1 item
  41. sodium channel2item
  42. TRPV1 item
  43. NTPDases1 item
  44. Calmodulins1 item
  45. TRPA1 item
  46. F1 Fo-ATPase1 item
  47. AMPA Receptors1 item
  48. mitochondrial pyruvate carrier (MPC)1 item
  49. Protein Tyrosine Phosphatases1 item
  50. alkaline phosphatases1 item
  51. ATPases1 item
  52. benzodiazepine receptor1 item
  53. glutamate release1 item
  54. NHE1 item
  55. GABAA receptor1 item
  56. Ca2 -ATPases1 item
Reported Experiments
  1. Animal Experiments73item
  2. Cell Experiments66item
Related Disease
  1. Acute Myeloid Leukemia1 item
  2. Anesthesia2item
  3. Breast Cancer1 item
  4. Cancer10item
  5. Epilepsy3item
  6. Glioma1 item
  7. Heart Failure3item
  8. Leukemia1 item
  9. Lymphoma2item
  10. Non-small Cell Lung Cancer2item
  11. Non-small Cell Lung Carcinoma2item
  12. Ovarian Cancer1 item
  13. Type 2 Diabetes5item