Isradipine (Dynacirc)
Catalog No.
A8453
Calcium channel blocker
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Isradipine (Dynacirc; CAS 75695-93-1) is a small molecule antagonist belonging to the dihydropyridine class of calcium channel blockers. It functions primarily by inhibiting L-type voltage-gated calcium channels, thereby decreasing intracellular calcium influx into cardiac and vascular smooth muscle cells. This inhibitory effect relaxes vascular smooth muscle tissue, leading to vasodilation and subsequent reduction in systemic blood pressure. In biomedical research, isradipine is studied for its potential neuroprotective properties related to calcium-mediated excitotoxicity, offering implications for conditions associated with neuronal calcium imbalance.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 371.39 |
| Cas No. | 75695-93-1 |
| Formula | C19H21N3O5 |
| Solubility | ≥12.55 mg/mL in DMSO; ≥16.43 mg/mL in EtOH with ultrasonic; ≥2.71 mg/mL in H2O with gentle warming and ultrasonic |
| Chemical Name | 3-O-methyl 5-O-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
| SDF | Download SDF |
| Canonical SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OC |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
