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Mibefradil

Catalog No.
A3604
Calcium channel blocker
Grouped product items
SizePriceStock Qty
10mg
$170.00
Please inquire
50mg
$745.00
Please inquire
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Mibefradil (CAS 116644-53-2) is a calcium channel antagonist exhibiting preferential inhibition of T-type calcium channels. It demonstrates moderate selectivity with reported IC50 values of approximately 2.7 μM for T-type Ca2? channels and 18.6 μM for L-type channels, thus predominantly targeting low-voltage activated calcium currents. Due to its mechanism of action, mibefradil has clinical relevance in cardiovascular research and is utilized experimentally for investigating T-type calcium channel involvement in hypertension and chronic angina pectoris.

Chemical Properties

StorageStore at -20°C
M.Wt495.63
Cas No.116644-53-2
FormulaC29H38FN3O3
SynonymsRo 40-5967
Solubility≥49.6 mg/mL in DMSO; ≥53.4 mg/mL in EtOH with gentle warming; ≥96.8 mg/mL in H2O with gentle warming
Chemical Name2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate
SDFDownload SDF
Canonical SMILESCC(C1C2=C(C=C(F)C=C2)CCC1(OC(COC)=O)CCN(CCCC3=NC4=CC=CC=C4N3)C)C
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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