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Signaling Pathways

Signaling Pathways

A4461 Bax inhibitor peptide V5

Target: Bax

Summary: Bax inhibitor

≥29.35 mg/mL
A4465 MIM1
1 Citation

Target: Mcl-1

Summary: Mcl-1 Inhibitor

insoluble in EtOH; insoluble in H2O; ≥12.15 mg/mL
B4902 (+)-Apogossypol

Target: Bcl-2

Summary: inhibitor of Bcl-2 family proteins

insoluble in H2O; ≥16.2 mg/mL
B5846 Radotinib(IY-5511)

Target: PDGFR|Bcr-Abl

Summary: Bcr-Abl tyrosine kinase inhibitor

≥13.73 mg/mL
A8737 S63845
11 Citation

Target: MCL1

Summary: MCL1 inhibitor
B1080 Marinopyrrole A

Target: Mcl-1

Summary: Selective Mcl-1 inhibitor

Soluble in DMSO
A8168 HA14-1

Target: Bcl-2

Summary: Bcl-2 inhibitor,potent and cell-permeable

insoluble in H2O; ≥20.45 mg/mL
A8194 ABT-199
14 Citation

Target: Bcl-2

Summary: Bcl-2 inhibitor,potent and selective

≥43.42 mg/mL
A3007 ABT-263 (Navitoclax)
15 Citation

Target: Bcl-2|Bcl-w

Summary: Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w

≥48.73 mg/mL
A4234 TW-37
1 Citation

Target: Bcl-2|Bcl-xl|Mcl-1

Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1

insoluble in H2O; ≥19.75 mg/mL