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Signaling Pathways

Signaling Pathways

B4902 (+)-Apogossypol

Target: Bcl-2

Summary: inhibitor of Bcl-2 family proteins

insoluble in H2O; ≥16.2 mg/mL
B5846 Radotinib(IY-5511)

Target: PDGFR|Bcr-Abl

Summary: Bcr-Abl tyrosine kinase inhibitor

≥13.73 mg/mL
B5978 BDA-366

Target: Bcl-2

Summary: Selective antagonist of BCL2 BH4 domain

≥50.4 mg/mL
B6011 A-1210477
2 Citation

Target: Mcl-1

Summary: MCL-1 inhibitor

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
A8737 S63845
11 Citation

Target: MCL1

Summary: MCL1 inhibitor
B6094 BH3I-1

Summary: Bcl-2 or Bcl-XL inhibitor

≥40 mg/mL
B1080 Marinopyrrole A

Target: Mcl-1

Summary: Selective Mcl-1 inhibitor

Soluble in DMSO
A8168 HA14-1

Target: Bcl-2

Summary: Bcl-2 inhibitor,potent and cell-permeable

insoluble in H2O; ≥20.45 mg/mL
N2135 Gossypol
2 Citation

Target: Dehydrogenase

Summary: PAF inhibitor;anti-fertility and anti-cancer

≥25.95 mg/mL
A8194 ABT-199
14 Citation

Target: Bcl-2

Summary: Bcl-2 inhibitor,potent and selective

≥43.42 mg/mL