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Signaling Pathways

Items 41-50 of 51

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  1. MIM1
    A4465 MIM1
     1 Citation
    Target: Mcl-1
    Summary: Mcl-1 Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥12.15 mg/mL
  2. Mitomycin C
    A4452 Mitomycin C
     3 Citation
    Summary: Inhibits DNA synthesis,antibiotic and antitumor agent
      insoluble in H2O; insoluble in EtOH; ≥16.7 mg/mL
  3. NSC 687852 (b-AP15)
    A4453 NSC 687852 (b-AP15)
    Target: Deubiquitinating enzymes (DUBs)
    Summary: 19S regulatory particle Inhibitor
      insoluble in EtOH; insoluble in H2O; ≥20.95 mg/mL
  4. Regorafenib
    A8236 Regorafenib
     4 Citation
    Target: Raf|VEGFR|PDGFR|c-Kit|RET
    Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
      ≥25.04 mg/mL
  5. VX-765
    A8238 VX-765
     1 Citation
    Target: Caspases
    Summary: Caspase-1 inhibitor,potent and selective
      insoluble in H2O; ≥313 mg/mL
  6. Cycloheximide
    A8244 Cycloheximide
     8 Citation
    Summary: Antibiotic,inhibitor of protein synthesis in eukaryotes
      ≥14.05 mg/mL
  7. WEHI-539 hydrochloride
    A8634 WEHI-539 hydrochloride
     1 Citation
    Summary: Bcl-xL inhibitor,high affinity and selective
      ≥28.55 mg/mL
  8. CID 755673
    A8678 CID 755673
    Target: PKD
    Summary: PKD inhibitor
  9. AMG232
    A8804 AMG232
     2 Citation
    Target: p53-MDM2 interaction
    Summary: p53-MDM2 inhibitor, novel
      Soluble in DMSO
  10. Z-IETD-FMK
    B3232 Z-IETD-FMK
     12 Citation
    Target: Caspases
    Summary: Caspase-8 inhibitor
      ≥32.73 mg/mL

Items 41-50 of 51

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Category
  1. Caspase11item
  2. Apoptosis Inducers8item
  3. Bcl-2 Family14item
  4. Bcl-xL4item
  5. c-RET2item
  6. IAP4item
  7. KEAP1-Nrf22item
  8. MDM21 item
  9. p533item
  10. PC-PLC1 item
  11. PKD1 item
  12. Survivin1 item
  13. Thymidylate Synthase1 item
  14. TNF-α4item
  15. Other Apoptosis1 item
Reversibility
  1. Reversible1 item
  2. Irreversible6item
Target
  1. Caspases11item
  2. Proteasome1 item
  3. Histone Deacetylases (HDACs)1 item
  4. Inhibitor of apoptosis proteins (IAP)3item
  5. Bcl-26item
  6. Raf1 item
  7. Bcl-xl3item
  8. MDM22item
  9. VEGFR2item
  10. PDGFR2item
  11. c-Kit1 item
  12. RET1 item
  13. Mcl-15item
  14. Bcr-Abl1 item
  15. Nrf21 item
  16. Deubiquitinating enzymes (DUBs)1 item
  17. RIP kinases1 item
  18. Survivin1 item
  19. Dehydrogenase1 item
  20. Mixed lineage kinase domain-like protein (MLKL)1 item
  21. COX1 item
  22. iNOS1 item
  23. TRP Channel1 item
  24. Apoptosis Inducers1 item
  25. angiogenesis1 item
  26. p53-MDM2 interaction1 item
  27. PC-PLC1 item
  28. PKD1 item
  29. MCL11 item
  30. Bcl-w1 item
Reported Experiments
  1. Animal Experiments41item
  2. Cell Experiments25item
Related Disease
  1. Acute Myeloid Leukemia1 item
  2. Adrenocortical Carcinoma1 item
  3. Autoimmune Diseases1 item
  4. Breast Cancer9item
  5. Cancer33item
  6. Chronic Lymphocytic Leukemia1 item
  7. Chronic Myeloproliferative Disorders1 item
  8. Colon Cancer4item
  9. Colorectal Cancer3item
  10. Glioblastoma4item
  11. Hepatocellular Carcinoma1 item
  12. Inflammatory Diseases1 item
  13. Lung Cancer3item
  14. Lymphoma4item
  15. Melanoma2item
  16. Multiple Myeloma2item
  17. Myelofibrosis1 item
  18. Myeloma1 item
  19. Neuroblastoma1 item
  20. Non-small Cell Lung Cancer4item
  21. Ovarian Cancer1 item
  22. Pain Relief1 item
  23. Pancreatic Cancer3item
  24. Prostate Cancer5item
  25. Pulmonary Fibrosis1 item
  26. Rheumatoid Arthritis1 item
  27. Soft Tissue Sarcoma1 item
  28. Testicular Cancer1 item