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Signaling Pathways

Signaling Pathways

A8232 Nilotinib(AMN-107)
1 Citation

Target: Bcr-Abl

Summary: Bcr-Abl kinase inhibitor,selective

≥26.5 mg/mL
A8249 SB 431542
2 Citation

Summary: ALK inhibitor
A1670 Enzastaurin (LY317615)
2 Citation

Target: PKC

Summary: PKC beta inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
A1352 Zoledronic Acid

Target: Farnesyl Diphosphate Synthases

Summary: Potent nitrogen-containing bisphosphonates

insoluble in DMSO; insoluble in H2O; insoluble in EtOH
A2133 Saracatinib (AZD0530)
3 Citation

Target: Src

Summary: Src/Abl inhibitor,potent and selective

≥27.1 mg/mL
A8301 GW788388

Summary: ALK5 inhibitor,potent and selective

≥21.25 mg/mL
A8310 PF-562271
1 Citation

Target: FAK|Pyk2

Summary: ATP-competitive FAK inhibitor, reversible

≥25.35 mg/mL
A8348 LY2157299
2 Citation

Summary: TGF-βR1 inhibitor,potent and selective

insoluble in H2O; ≥18.45 mg/mL
A8345 PF-562271 HCl

Target: FAK|Pyk2

Summary: FAK/Pyk2 inhibitor

≥26.35 mg/mL
A8341 Go 6976

Target: PKC

Summary: PKCα/PKCβ1 inhibitor

≥15.77 mg/mL