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Signaling Pathways

Signaling Pathways

A3221 Bardoxolone methyl

Target: Nrf2

Summary: IKK inhibitor, potent antioxidant inflammation modulator

≥25.3 mg/mL
A3320 CO-1686 (AVL-301)
1 Citation

Target: EGFR

Summary: EGFR inhibitor

≥27.8 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
A3741 Pyridone 6

Target: JAK

Summary: Pan-JAK inhibitor

insoluble in H2O; ≥15.45 mg/mL
A3937 XL019

Target: JAK

Summary: JAK2 inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥11.125 mg/mL