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Signaling Pathways

Signaling Pathways

A2689 Butein

Target: Src|STAT|EGFR|Angiotensin-Converting Enzymes (ACEs)|5-Lipoxygenases|PTK|enoyl-acyl-carrier protein reductase

Summary: Protein kinase inhibitor

insoluble in H2O; ≥13.6 mg/mL
A8317 Fludarabine Phosphate (Fludara)
2 Citation

Target: STAT

Summary: Inhibits STAT1 activation and DNA synthesis

insoluble in EtOH; ≥17.6 mg/mL
A8319 Dacomitinib (PF299804, PF299)

Target: ErbB

Summary: HER inhibitor

≥23.5 mg/mL
A8322 Neratinib (HKI-272)
1 Citation

Target: EGFR

Summary: HER2/EGFR inhibitor,potent and irreversible

insoluble in H2O; ≥13.93 mg/mL
A8357 AG-1478

Target: EGFR

Summary: EGFR inhibitor,potent and selective

insoluble in H2O; ≥15.8 mg/mL
B4970 HO-3867
1 Citation

Target: STAT

Summary: STAT3 inhibitor, selective

insoluble in EtOH; insoluble in H2O; ≥18.15 mg/mL
B1104 AZD-9291
1 Citation

Target: EGFR

Summary: Mutated forms EGFR inhibitor

≥24.98 mg/mL
B2283 Niclosamide

Target: STAT

Summary: Inhibitor of the STAT3 signaling pathway
A8197 Compound 56
1 Citation

Target: EGFR

Summary: REGFR inhibitor

insoluble in H2O; ≥16.95 mg/mL
A8199 PD153035 hydrochloride
1 Citation

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; insoluble in H2O; ≥3.97 mg/mL