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Signaling Pathways

Signaling Pathways

A8813 NSC697923

Target: Ub-conjugating enzyme (E2) complex

Summary: Inhibitor of E2 complex Ubc13-Uev1A,cell permeable and selective

insoluble in H2O; insoluble in EtOH; ≥26 mg/mL
B1492 PYR-41
2 Citation

Target: Proteasome

Summary: inhibitor of Ubiquitin-Activating Enzyme (E1)
B2168 NMS-873
3 Citation

Target: Valosin-containing protein (VCP)

Summary: VCP/p97 inhibitor,selective and allosteric

insoluble in H2O; ≥17.1 mg/mL
A8883 SAR405
22 Citation

Summary: Selective ATP-competitive inhibitor of Vps34

≥22.19 mg/mL
A8716 LY3009120

Target: Raf

Summary: pan-RAF and RAF dimer inhibitor

insoluble in H2O; insoluble in EtOH; ≥4.25 mg/mL
A8715 SBI-0206965
2 Citation

Target: ULK1

Summary: ULK1 inhibitor

≥24.47 mg/mL
B5873 Spautin-1
1 Citation

Target: Deubiquitinating enzymes (DUBs)|Autophagy

Summary: Novel autophagy inhibitor

insoluble in H2O; ≥13.5 mg/mL
B6026 VR23

Target: Proteasome

Summary: proteasome inhibitor

insoluble in EtOH; insoluble in H2O; ≥45.55 mg/mL
B1317 ML-323

Target: Deubiquitinating enzymes (DUBs)

Summary: USP1-UAF1 inhibitor
A3023 P005091
1 Citation

Target: Ubiquitin-specific proteases

Summary: Ubiquitin-specific protease 7 (USP7) inhibitor

insoluble in H2O; insoluble in EtOH; ≥17.4 mg/mL