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Signaling Pathways

Signaling Pathways

A5072 GSK690693

Target: Akt|PKC|PKG|PKA|Prk

Summary: Pan-AKT inhibitor,ATP-competitive and potent

≥21.25 mg/mL
A5653 AT7867

Target: Akt|PKA|p70 rsk

Summary: Akt1/2/3 and p70S6K/PKA inhibitor

≥16.9 mg/mL
A1387 AZD5363
3 Citation

Target: Akt

Summary: AKT inhibitor,pyrrolopyrimidine derived

≥21.45 mg/mL
A8309 Perifosine
1 Citation

Target: Akt

Summary: Akt inhibitor
A8499 PF-04691502

Target: Akt|PI3K|mTOR

Summary: PI3K/mTOR (FRAP) inhibitor

insoluble in H2O; insoluble in EtOH; ≥10.63 mg/mL
A8616 A-674563

Target: Cyclin-Dependent Kinases|Akt|GSK-3|ERK|PKC|PKA|RSK

Summary: Akt1/PKA/CDK2 inhibitor,potent and selective

insoluble in EtOH; ≥23.8 mg/mL
A8617 CCT128930 HCl

Target: Akt

Summary: AKT inhibitor

insoluble in H2O; ≥17.1 mg/mL
B6099 LY3023414

Target: Akt|PI3K|mTOR|DNA-PK

Summary: class I PI3K isoforms, mTOR and DNA-PK inhibitor

≥40.6 mg/mL
B2180 AS-252424

Target: Akt|PI3K

Summary: PI3Kγ inhibitor,novel and potent

insoluble in EtOH; insoluble in H2O; ≥30.5 mg/mL
B7105 10-DEBC hydrochloride

Target: Akt

Summary: Akt inhibitor

Soluble in DMSO