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Signaling Pathways

Items 51-60 of 234

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  1. Moxifloxacin HCl
    A5323 Moxifloxacin HCl
     1 Citation
    Target: Antibiotic
    Summary: Fluoroquinolone antibiotic
      insoluble in EtOH; ≥43.91 mg/mL
  2. Ofloxacin
    A5511 Ofloxacin
    Target: Topoisomerases|DNA gyrase
    Summary: Fluoroquinolones,antibiotics
      insoluble in H2O; insoluble in EtOH; ≥12.03 mg/mL
  3. VE-821
    A2521 VE-821
     2 Citation
    Summary: ATR kinase inhibitor
      ≥62.5 mg/mL
  4. KU-0060648
    A1769 KU-0060648
     1 Citation
    Target: PI3K|DNA-PK
    Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
  5. NU7441 (KU-57788)
    A8315 NU7441 (KU-57788)
     4 Citation
    Target: PI3K|DNA-PK
    Summary: DNA-PK inhibitor
      insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
  6. Fludarabine Phosphate (Fludara)
    A8317 Fludarabine Phosphate (Fludara)
     2 Citation
    Target: STAT
    Summary: Inhibits STAT1 activation and DNA synthesis
      insoluble in EtOH; ≥17.6 mg/mL
  7. Bleomycin Sulfate
    A8331 Bleomycin Sulfate
     1 Citation
    Summary: Chemotherapy agent, induces DNA strand break
      ≥125 mg/mL
  8. KU-60019
    A8336 KU-60019
     2 Citation
    Target: ATM/ATR
    Summary: ATM kinase inhibitor,potent and selective
      ≥27.4 mg/mL
  9. CX-5461
    A8337 CX-5461
     2 Citation
    Summary: Pol I-mediated rRNA synthesis inhibitor
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO
  10. Gemcitabine
    A8437 Gemcitabine
     1 Citation
    Summary: inhibitor of DNA synthesis
      ≥11.75 mg/mL

Items 51-60 of 234

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Category
  1. MTH14item
  2. PARP32item
  3. ATM/ATR10item
  4. DNA Alkylating9item
  5. DNA Ligases3item
  6. DNA Methyltransferase2item
  7. DNA-PK8item
  8. DNA Synthesis52item
  9. HDAC55item
  10. Nucleoside Antimetabolite/Analogue13item
  11. Telomerase5item
  12. Topoisomerase38item
  13. tankyrase5item
Specificity
  1. Selective72item
Reversibility
  1. Reversible4item
Target
  1. Histone Deacetylases (HDACs)34item
  2. PI3K5item
  3. MDM21 item
  4. mTOR1 item
  5. Thymidylate Synthase2item
  6. STAT1 item
  7. Estrogen and Related Receptors1 item
  8. EGFR1 item
  9. Tankyrases1 item
  10. DNA-PK4item
  11. TNKS1 item
  12. Topoisomerases11item
  13. ErbB1 item
  14. DNA Methyltransferases1 item
  15. PARP7item
  16. ATM/ATR6item
  17. AP endonucleases1 item
  18. HSV2item
  19. Synthases/Synthetases1 item
  20. RNA Polymerases1 item
  21. FoxM11 item
  22. O6-methylguanine-DNA-methyl-transferase (MGMT)1 item
  23. Adenine receptors1 item
  24. RNA synthesis1 item
  25. FPTase1 item
  26. p531 item
  27. HDAC1 item
  28. KDM1 item
  29. PPAR1 item
  30. HCV polymerase1 item
  31. Antibiotic1 item
  32. DNA Alkylating2item
  33. telomerase1 item
  34. Telomerases1 item
  35. Ribonucleotide Reductases1 item
  36. PTK1 item
  37. Adenosine Deaminases1 item
  38. DNA gyrase1 item
  39. DNA Ligases1 item
  40. 5-HT1 item
  41. PHF1 item
  42. ATM2item
  43. MTH11 item
Reported Experiments
  1. Animal Experiments95item
  2. Cell Experiments79item
Related Disease
  1. Acute Myelogenous Leukemia2item
  2. Acute Myeloid Leukemia2item
  3. Bladder Cancer4item
  4. Breast Cancer19item
  5. Cancer68item
  6. Chronic Lymphocytic Leukemia1 item
  7. Colon Cancer10item
  8. Colon Carcinoma1 item
  9. Colorectal Cancer7item
  10. Dyskinesia1 item
  11. Epilepsy1 item
  12. Friedreich's Ataxia1 item
  13. Glioblastoma2item
  14. Glioma2item
  15. HCV1 item
  16. Hepatic Cancer1 item
  17. Hepatocellular Carcinoma3item
  18. HIV Infections1 item
  19. Inflammatory Diseases1 item
  20. Leukemia7item
  21. Liver Cancer1 item
  22. Lung Cancer6item
  23. Lymphoma7item
  24. Melanoma5item
  25. Multiple Myeloma3item
  26. Myeloma2item
  27. Neuroblastoma2item
  28. Neuronal Protection1 item
  29. Non-small Cell Lung Cancer3item
  30. Ovarian Cancer8item
  31. Pancreatic Cancer4item
  32. Prostate Cancer10item
  33. Renal Cancer1 item
  34. Renal Cell Carcinoma2item
  35. Testicular Cancer1 item