Ofloxacin
Catalog No.
A5511
Fluoroquinolones,antibiotics
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Ofloxacin (CAS: 82419-36-1) is a small-molecule inhibitor targeting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, thereby blocking bacterial DNA replication and transcription. In in vitro studies, ofloxacin demonstrates inhibitory activity, with reported IC50 values ranging from 0.5 to 10 μg/mL depending on bacterial strain variability and experimental conditions. Ofloxacin holds research potential in microbiological and pharmaceutical studies, such as bacterial resistance research, evaluation of bacterial enzyme inhibition, susceptibility assay validation, and investigation of bacterial gene regulation and replication mechanisms.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 361.37 |
| Cas No. | 82419-36-1 |
| Formula | C18H20FN3O4 |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥12.03 mg/mL in DMSO with gentle warming |
| Chemical Name | 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid |
| SDF | Download SDF |
| Canonical SMILES | CC1N(C=C(C(O)=O)C(c2cc(F)c3N4CCN(C)CC4)=O)c2c3OC1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
