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Signaling Pathways

Signaling Pathways

A2024 PD168393

Target: PDGFR|FGFR|EGFR|PKC|insulin

Summary: EGFR inhibitor
A8319 Dacomitinib (PF299804, PF299)

Target: ErbB

Summary: HER inhibitor

≥23.5 mg/mL
A8322 Neratinib (HKI-272)
1 Citation

Target: EGFR

Summary: HER2/EGFR inhibitor,potent and irreversible

insoluble in H2O; ≥13.93 mg/mL
A8696 FIIN-2

Target: FGFR

Summary: Irreversible inhibitor of FGFR

≥31.75 mg/mL
B1104 AZD-9291
1 Citation

Target: EGFR

Summary: Mutated forms EGFR inhibitor

≥24.98 mg/mL