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Signaling Pathways

Items 161-170 of 241

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  1. BIBR 953 (Dabigatran, Pradaxa)
    A4077 BIBR 953 (Dabigatran, Pradaxa)
    Summary: Thrombin inhibitor,potent,reversible and direct
      insoluble in DMSO; insoluble in EtOH; insoluble in H2O
  2. Fosinopril sodium
    A4079 Fosinopril sodium
    Summary: ACE inhibitor
      Soluble in DMSO
  3. Olmesartan medoxomil
    A4082 Olmesartan medoxomil
    Summary: AT1 receptor antagonist
      ≥21.1 mg/mL
  4. Danoprevir (RG7227)
    A4024 Danoprevir (RG7227)
    Target: HCV Proteases
    Summary: HCV NS3/4A protease inhibitor
      ≥32.6 mg/mL
  5. Lopinavir
    A8204 Lopinavir
    Summary: HIV protease inhibitor,highly potent
      ≥31.45 mg/mL
  6. Telaprevir (VX-950)
    A4031 Telaprevir (VX-950)
    Target: HCV NS3-4A protease
    Summary: HCV NS3-4A protease inhibitor
      ≥32.95 mg/mL
  7. VX-222 (VCH-222, Lomibuvir)
    A4032 VX-222 (VCH-222, Lomibuvir)
    Target: HCV polymerase
    Summary: NNI of HCV RNA polymerase
      ≥44.6 mg/mL
  8. Glimepiride
    A4033 Glimepiride
    Target: Inward Rectifier Potassium (Kir) Channels
    Summary: Sulfonylurea compound
      ≥21.45 mg/mL
  9. Linagliptin (BI-1356)
    A4034 Linagliptin (BI-1356)
    Summary: DDP-4 inhibitor,highly potent and competitive
      insoluble in H2O; insoluble in EtOH; ≥17.85 mg/mL
  10. Sitagliptin phosphate monohydrate
    A4036 Sitagliptin phosphate monohydrate
     5 Citation
    Target: DPP-4
    Summary: Potent DPP-4 inhibitor
      ≥23.8 mg/mL

Items 161-170 of 241

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Category
  1. Caspase25item
  2. Aminopeptidase8item
  3. ACE9item
  4. Calpains11item
  5. Carboxypeptidase4item
  6. Cathepsin12item
  7. DPP-418item
  8. Elastase10item
  9. Gamma Secretase18item
  10. HCV Protease15item
  11. HSP25item
  12. HIV Integrase12item
  13. HIV Protease13item
  14. MMP25item
  15. NS3/4a protease4item
  16. Serine Protease9item
  17. Thrombin14item
  18. Urokinase2item
  19. Other Proteases11item
  20. Tyrosinases1 item
Specificity
  1. Selective80item
  2. Non-Selective1 item
Reversibility
  1. Reversible14item
  2. Irreversible13item
Target
  1. Caspases13item
  2. Proteasome1 item
  3. Cathepsins11item
  4. MMP6item
  5. Factor Xa3item
  6. Thymidylate Synthase1 item
  7. Aminopeptidases3item
  8. HSP9012item
  9. Notch1 item
  10. thrombin1 item
  11. Renin1 item
  12. HIV proteases1 item
  13. Pepsins1 item
  14. Serine Proteases2item
  15. Calpains5item
  16. HCV Proteases3item
  17. Trypsins1 item
  18. Trypsin1 item
  19. Chymotrypsin1 item
  20. Kallikrein1 item
  21. Trypsinogen1 item
  22. HIV-1 gp1201 item
  23. HIV Integrases2item
  24. Urokinases1 item
  25. Inward Rectifier Potassium (Kir) Channels1 item
  26. Papains1 item
  27. DPP-45item
  28. Nonstructural protein 5B (NS5B)1 item
  29. ADAMs1 item
  30. Dipeptidyl-peptidase II1 item
  31. metalloprotease1 item
  32. cysteine protease2item
  33. HCV polymerase2item
  34. Subtilisin/Kex2p-like proprotein convertase1 item
  35. Elastases1 item
  36. integrase1 item
  37. HCV NS3-4A protease1 item
  38. NE1 item
Reported Experiments
  1. Animal Experiments90item
  2. Cell Experiments69item
Related Disease
  1. Acute Lung Injury1 item
  2. Acute Myeloid Leukemia1 item
  3. Breast Cancer11item
  4. Cancer35item
  5. Chronic Lymphocytic Leukemia1 item
  6. Clear Cell Renal Cell Carcinoma1 item
  7. Colon Cancer2item
  8. Diabetes3item
  9. Glioma1 item
  10. HCV3item
  11. Hepatitis C4item
  12. HIV4item
  13. HIV Infections2item
  14. Inflammatory Diseases1 item
  15. Lung Cancer3item
  16. Lymphoma1 item
  17. Melanoma7item
  18. Multiple Myeloma2item
  19. Neuroblastoma1 item
  20. Non-small Cell Lung Cancer2item
  21. Osteoporosis1 item
  22. Ovarian Cancer4item
  23. Pancreatic Cancer3item
  24. Prostate Cancer3item
  25. Psoriasis1 item
  26. Renal Cell Carcinoma1 item
  27. Rheumatoid Arthritis3item
  28. Squamous Cell Carcinoma1 item
  29. Type 2 Diabetes1 item