JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

Home
Search results for: 'sirtuin modulator'

Search results for: 'sirtuin modulator'

BA6659 Basmisanil

Summary: Basmisanil (RG1662) is a highly selective alpha-subunit-containing GABAA receptor (GABAAα5)-negative modulator with oral activity.
BA6755 GNE-9278

Summary: GNE-9278 is a highly selective orthosteric modulator that acts on the GluN1 transmembrane structural domain (TMD).
BA8589 BPN-15606

Summary: BPN-15606 is a potent oral activity modulator (GSM) that attenuates SHSY5Y neuroblastoma cell production.
BA8590 PF-06648671

Summary: PF-06648671 is a novel, blood-brain barrier permeable, orally active gamma secretase modulator (GSM).
BA1841 BA-53038B

Summary: BA-53038B is a core protein alteration modulator (CpAM) that binds to the HAP pocket and regulates coat assembly.
BA5597 VU6001966

Summary: VU6001966 is a potent negative-conversion modulator that crosses the blood-brain barrier, with mGlu2 and mGlu3's of 78nM and >30μM, respectively.
BA6619 Bamocaftor

Summary: Bamocaftor (VX-659) is a cystic fibrosis transmembrane conductance modulator corrector designed to restore protein function.
BA6813 BNC210

Summary: BNC210 (H-Ile-Trp-OH) is an orally effective, negative alteration modulator (NAM) without significant side effects.
BA6874 Rimtuzalcap

Summary: Rimtuzalcap (CAD-1883) is a first-of-its-kind, selective small conductance calcium-activated potassium channel (channel) orthosteric modulator.
BA5507 VU0467485

Summary: VU0467485 (AZ13713945) is a potent, selective, orally bioavailable muscarinic acetylcholine receptor 4 orthosteric modulator (PAM).