VU0467485
Catalog No.
BA5507
VU0467485 (AZ13713945) is a potent, selective, orally bioavailable muscarinic acetylcholine receptor 4 orthosteric modulator (PAM).
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VU0467485 (AZ13713945) is a potent, selective, orally bioavailable muscarinic acetylcholine receptor 4 orthosteric modulator (PAM).VU0467485 (AZ13713945) enhances the activity of ACh at M4, with 26.6 nM and 78.8 nM at rat and human M4 receptors, respectively. VU0467485 (AZ13713945) shows M4 selectivity for human and rat M1/2/3/5.VU0467485 (AZ13713945) shows moderate to high CNS penetration with antipsychotic-like activity.
Physical Appearance | A solid |
Storage | -20°C |
M.Wt | 360.41 |
Cas No. | 1451994-10-7 |
Formula | C17H17FN4O2S |
Synonyms | AZ13713945 |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |