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Poly (ADP-ribose) polymerases (PARPs) is a large family of proteins with a conserved catalytic domain that catalyze an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins leading to the survival of injured proliferating cells. So far, a total number of 18 human PARP proteins encoded by different genes have been identified, including PARP-1 to PARP-4, PARP-5a, PARP-5b, PARP-5c and PARP-6 to PARP-16. The general structural of PARP proteins has been revealed through the extensive study of the founding family member PARP-1, which is characterized by the presence of four functional domains, including a DNA-binding domain, a caspase-cleaved domain, an automodification domain and a catalytic domain.


  1. Cat.No. Product Name Information
  2. A3002 ABT-888 (Veliparib) Top Seller Potent PARP inhibitor
  3. A1877 XAV-939 Top Seller Tankyrase 1/2 inhibitor
  4. A4164 AZD2461 Novel PARP inhibitor
  5. A4159 PJ34 hydrochloride Top Seller PARP inhibitor,potent and cell-permeable
  6. A4158 AG-14361 Potent PARP1 inhibitor
  7. A4157 Iniparib (BSI-201) PARP1 inhibitor,intravenously adminsitered
  8. A4156 Rucaparib (AG-014699,PF-01367338) Top Seller Potent PARP inhibitor
  9. A4154 Olaparib (AZD2281, Ku-0059436) Top Seller Potent PARP1/PARP2 inhibitor
  10. A4153 BMN 673 Top Seller Potent PARP inhibitor
  11. A8893 Rucaparib (free base) Potent PARP inhibitor
  12. A8808 ME0328 PARP inhibitor,potent and selective
  13. A8601 Tankyrase Inhibitors (TNKS) 49 Tankyrase inhibitor
  14. A8600 Tankyrase Inhibitors (TNKS) 22 Tankyrase inhibitor
  15. A4529 JW 55 Top Seller PARP domain inhibitor
  16. A3729 PJ34 PARP-l inhibitor
  17. A4161 INO-1001 Potent PARP inhibitor
  18. A4531 WIKI4 Inhibitor of Wnt/ß-Catenin signaling and tankyrase
  19. A4530 NU 1025 PARP inhibitor,potent and novel
  20. A4527 DR 2313 PARP inhibitor
  21. A4526 BYK 49187 Potent PARP-1/PARP-2 inhibitor
  22. A4525 BYK 204165 PARP-1 inhibitor,potent and selective
  23. A3617 MK-4827 PARP-1/-2 inhibitor,potent and selective
  24. A3246 BMN-673 8R,9S PARP inhibitor
  25. A4163 UPF 1069 Selective PARP2 inhibitor
  26. A4160 A-966492 PARP-1/-2 inhibitor, highly potent
  27. A4524 4-HQN PARP inhibitor
  28. A4528 EB 47 Potent PARP-1 inhibitor
  29. B1163 MK-4827 hydrochloride PARP1/PARP2 inhibitor
  30. B1164 MK-4827 tosylate PARP1/PARP2 inhibitor
  31. B3393 MK-4827 Racemate selective inhibitor of PARP1/PARP2
  32. A3958 Veliparib dihydrochloride PARP-1/PARP-2 inhibitor