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Dehydrogenase

Dehydrogenases, belonging to the class of oxidoreductases which catalyze donor-acceptor reactions to transfer electron molecules from the oxidant to the reluctant, are a diverse group of enzymes that are able to transfer one or more hydrides (H-) from a substrate to an electron acceptor, such as nicotinamide adenine dinucleotide (NAD+), nicotinamide adenine dinucleotide phosphate (NADP+) or Riboflavin, through oxidation and reduction. Three commonly studied dehydrogenase enzymes include alcohol dehydrogenase (ADH) which catalyzes the reduction of acetylaldehyde to ethanol in plant cells, succinate dehydrogenase which oxidizes succinate to fumarate, and lactate dehydrogenase which catalyzes the reversible oxidation of lactate to pyruvate.

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  1. Cat.No. Product Name Information
  2. C4497 6-Aminonicotinamide 6-phosphogluconate dehydrogenase inhibitor
  3. C5603 A-771726 dihydroorotate dehydrogenase inhibitor
  4. B7805 AG-120 mutant IDH1 inhibitor
  5. B7804 AG-221 (Enasidenib) mutant isocitrate dehydrogenase 2 (IDH2) inhibitor
  6. A4339 AGI-5198 IDH1 inhibitor against R132 mutant,selective and cell-permeable
  7. A3146 AGI-6780 IDH2/R140Q mutation inhibitor
  8. B5508 Alda 1 ALDH2 activator
  9. B6104 BVT 2733 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor
  10. A8721 CBR-5884 selective inhibitor of PHGDH
  11. B5354 CGP 3466B maleate GAPDH inhibitor

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