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Carbonic Anhydrase

Carbonic anhydrases (CAs) are a family of zinc containing metalloproteins that catalyze the reversible conversion of carbon dioxide (CO2) to bicarbonate with the releasing of a proton.  Being encoded by three distinct and evolutionarily unrelated gene families, CA enzymes are divided into three subfamilies, α-CAs (in vertebrates, eubacteria, algae and cytoplasm of green plants), β-CAs (in eubacteria, algae and chloroplasts of both mono- and di-cotyledons) and γ-CAs (in Archaea and some eubacteria). Through extensive studies, fourteen different CA isozymes have been identified in mammals, including four cytosolic isozymes (CA I-III and CA VII), four membrane-bound isozymes (CA IV, CA IX, CA XII and CA XIV), one mitochondrial isozyme (CA V) and one secreted isozyme (CA VI).

  1. Cat.No. Product Name Information
  2. B6125 Acetazolamide carbonic anhydrase (CA) inhibitor
  3. B6154 Benzenesulfonamide carbonic anhydrase inhibitor
  4. A4359 Brinzolamide CA II inhibitor
  5. A4357 Dorzolamide HCl Carbonic anhydrase inhibitor
  6. A4364 Methazolamide Carbonic anhydrase inhibitor
  7. A4362 Tioxolone CAI inhibitor
  8. A4360 Topiramate GluR5 receptor antagonist,anticonvulsant
  9. A4358 U-104 CAIX inhibitor

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