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Metabolism

  1. Cat.No. Product Name Information
  2. A8703 Isosafrole A stiripentol analog, a potent LDH inhibitor.
  3. A8704 Stiripentol An LDH inhibitor
  4. B4750 (-)-p-Bromotetramisole Oxalate ALP inhibitor, potent and non-specific
  5. A4300 GW9662 PPARγ antagonist
  6. A3152 Aleglitazar PPARα/PPARγagonist
  7. A3216 Balaglitazone PPAR-γ partial agonist
  8. A3453 GW1929 Potent PPARγ agonist
  9. A3498 Inolitazone PPARgamma agonist
  10. A3893 Troglitazone Selective PPARγ agonist
  11. A4324 Pioglitazone HCl PPARγ agonist
  12. A4310 Rosiglitazone HCl PPARγ agonist
  13. A4301 T0070907 Human PPARγ antagonist,potent and selective
  14. A4302 Rosiglitazone maleate PPARγ agonist,high-affinity and selective,potent insulin sensitizer
  15. A4303 GSK3787 PPARβ/δ antagonist,novel and irreversible
  16. A4304 Rosiglitazone Potent PPARγ agonist
  17. A4305 WY-14643 (Pirinixic Acid) PPARα agonist,selective and highly potent
  18. A4306 Ciprofibrate PPARα agonist
  19. A4307 GW0742 PPARδ/β agonist,potent and selective
  20. A4309 GW501516 PPARβ agonist,selective and potent
  21. B7553 Tesaglitazar Dual-specificity PPARα/γ agonist
  22. B7609 CP 775146 PPARα agonist
  23. B5581 SR 1664 inhibits Cdk5-mediated PPARγ phosphorylation, antidiabetic agent
  24. A8957 AUDA Potent epoxide hydrolase inhibitor/PPARα activator
  25. B6128 Fenofibric acid ppar inhibitor, lipid-lowering agent
  26. B7471 S26948 PPARγ agonist
  27. B7406 GSK 0660 PPARδ antagonist
  28. A3499 Inolitazone dihydrochloride PPARγ agonist,high-affinity and novel
  29. A3536 L-165041 PPARβ/δ agonist,cell permeable,potent and selective
  30. B7010 15-deoxy-Δ-12,14-Prostaglandin J2 PPARγ agonist
  31. B6681 Ciglitazone PPARγ agonist
  32. B6691 BADGE PPARγ antagonist
  33. B6929 SR 202 PPAR antagonist
  34. B6955 nTZDpa PPARγ partial agonist
  35. B6826 GW 7647 PPARα agonist
  36. B2117 Pioglitazone PPAR agonist
  37. B1943 Fenofibrate PPARα agonist
  38. B1947 Gemfibrozil PPARα activator
  39. B3610 Clofibrate PPAR agonist
  40. A1659 Dutasteride 5-alpha-reductase inhibitor
  41. A5143 Finasteride Inhibitor of Type II 5α-reductase
  42. B1195 Finasteride acetate 5α-reductase inhibitor
  43. B3422 U-73122 inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase)
  44. B1207 Zileuton sodium 5-lipoxygenase and leukotrienes inhibitor
  45. A5384 Zileuton 5-lipoxygenase (5-LOX) inhibitor, orally active
  46. A2486 Malotilate Stimulates hepatocyte regeneration
  47. A3277 Capadenoson Adenosine A1 receptor agonist
  48. B6662 EHNA hydrochloride cGMP-stimulated phosphodiesterase (PDE2) and adenosine deaminase inhibitor
  49. B5619 1-Deazaadenosine adenosine deaminase inhibitor
  50. A4355 Tosedostat (CHR2797) Aminopeptidase inhibitor
  51. A1718 Posaconazole Sterol C14ɑ demethylase inhibitor
  52. B1225 Posaconazole hydrate C14ɑ demethylase inhibitor
  53. A4357 Dorzolamide HCl Carbonic anhydrase inhibitor
  54. A4358 U-104 CAIX inhibitor
  55. A4359 Brinzolamide CA II inhibitor
  56. A4364 Methazolamide Carbonic anhydrase inhibitor
  57. A4360 Topiramate GluR5 receptor antagonist,anticonvulsant
  58. B6125 Acetazolamide carbonic anhydrase (CA) inhibitor
  59. B6154 Benzenesulfonamide carbonic anhydrase inhibitor
  60. A4362 Tioxolone CAI inhibitor
  61. A4376 Dalcetrapib (JTT-705, RO4607381) rhCETP inhibitor
  62. A4377 Evacetrapib (LY2484595) CETP inhibitor,potent and selective
  63. A4378 Torcetrapib CETP inhibitor
  64. A4375 Anacetrapib (MK-0859) RhCETP/mutant CETP(C13S) inhibitor
  65. A8430 Ezetimibe Cholesterol transport inhibitor
  66. A3404 Etomoxir (CPT)-1 and DGAT activity inhibitor
  67. A4313 Cobicistat (GS-9350) Selective CYP3A inhibitor
  68. B5990 Diosmetin CYP1A1 inhibitor
  69. B5963 7-Ethoxyresorufin Specific subtrate of CYP1A
  70. B5405 YM 511 aromatase (CYP19) inhibitor
  71. B7714 3-Cyano-7-ethoxycoumarin Fluorescent P450 substrate
  72. B6768 TMS cytochrome P450 1B1 inhibitor
  73. B5724 Pentoxyresorufin fluorometric cytochrome P450 substrate
  74. B5723 Methoxyresorufin fluorometric substrate of cytochrome P450
  75. B7737 ABT Cytochrome P450 inhibitor
  76. A3374 Dronedarone CYP3A4 and 2D6 inhibitor,moderate
  77. A4322 Clarithromycin CYP3A inhibitor, potent
  78. A4320 Voriconazole CYP51 inhibitor
  79. B4692 Dafadine-A DAF-9 cytochrome P450 inhibitor
  80. B4685 VT-464 racemate CYP17 lyase inhibitor
  81. B4684 VT-464 R enantiomer CYP17 lyase inhibitor
  82. B4683 VT-464 Human CYP17 lyase inhibitor
  83. A4351 PluriSIn #1 (NSC 14613) Top Seller SCD1 inhibitor
  84. A4348 Trilostane 3β-HSD inhibitor
  85. A4342 Gimeracil Dihydropyrimidine dehydrogenase inhibitor
  86. A4339 AGI-5198 Top Seller IDH1 inhibitor against R132 mutant,selective and cell-permeable
  87. A4336 Mycophenolate Mofetil IMPDH inhibitor
  88. B6104 BVT 2733 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor
  89. A3837 DL-α-Hydroxyglutaric acid disodium salt alpha hydroxy acid
  90. A1606 L-a-Hydroxyglutaric acid disodium salt salt form of L-α-Hydroxyglutaric acid
  91. B6124 Fomepizole competitive inhibitor of the enzyme alcohol dehydrogenase
  92. B7804 AG-221 (Enasidenib) mutant isocitrate dehydrogenase 2 (IDH2) inhibitor
  93. B7805 AG-120 mutant IDH1 inhibitor
  94. B7824 ML390 human DHODH inhibitor
  95. A8721 CBR-5884 selective inhibitor of PHGDH
  96. B4929 GSK 2837808A Potent, selective lactate dehydrogenase A (LDHA) inhibitor
  97. B4928 CVT 10216 reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2)
  98. A4333 CPI-613 PDH/α-KGDH inhibitor
  99. A3146 AGI-6780 IDH2/R140Q mutation inhibitor
  100. B4669 Vidofludimus DHODH inhibitor
  101. B7725 Methylmalonate reversible succinate dehydrogenase inhibitor
  102. B5697 WIN 18446 inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)
  103. B5716 Galloflavin human lactate dehydrogenase (LDH) inhibitor
  104. B5354 CGP 3466B maleate GAPDH inhibitor
  105. B5508 Alda 1 ALDH2 activator
  106. B5799 Qc 1 threonine dehydrogenase (TDH) inhibitor
  107. B5643 TC HSD 21 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor
  108. B1129 Mutant IDH1 inhibitor Potent mutant IDH1 R132H inhibitor
  109. A4347 Methotrexate Folate antagonist,inhibits DFHR
  110. A4350 Pralatrexate Antifolate,a folate analog
  111. A4353 Pyrimethamine DHFR inhibitor
  112. A4390 Pemetrexed Top Seller TS, DHFR,GARFT and AICARFT inhibitor
  113. A3707 Pemetrexed disodium hemipenta hydrate Antifolate and antimetabolite agent
  114. A3363 DGAT-1 inhibitor Diacylglycerol acyltransferase (DGAT1) inhibitor
  115. A3364 DGAT-1 inhibitor 2 Antiobesity agents
  116. A3542 LCQ-908 DGAT1 inhibitor
  117. A3140 ABT-046 DGAT-1 inhibitor,potent and selective
  118. A3215 AZD7687 DGAT inhibitor,potent and selective
  119. B4822 DGAT1-IN-1 potent DGAT1 inhibitor
  120. B4944 AZD 3988 diacylglycerol acyltransferase (DGAT-1) inhibitor
  121. A4335 Mildronate GBB hydroxylase inhibitor
  122. A4015 Disulfiram Dopamine β-hydroxylase inhibitor
  123. A4330 Isotretinoin Dopamine β-hydroxylase activator
  124. A4332 Nepicastat (SYN-117) HCl Dopamine-β-hydroxylase inhibitor
  125. B7346 PF 915275 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor
  126. B3588 AP-III-a4 enolase inhibitor
  127. B7356 PF 750 FAAH inhibitor
  128. B5714 SA 47 FAAH inhibitor
  129. B5704 SA 57 FAAH inhibitor
  130. B5562 TC-F 2 FAAH inhibitor
  131. B7701 JZL 195 Dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL)
  132. A3714 PF-04457845 FAAH inhibitor,potent and exquisitely selective
  133. A3571 LY2183240 Blocker of anandamide uptake,highly potent
  134. A4372 URB597 FAAH inhibitor,potent and selective
  135. A4361 JNJ-1661010 FAAH inhibitor,potent and selective
  136. B4931 TAK 21d Potent FAAH inhibitor
  137. B1245 FAAH inhibitor 1 Potent fatty acid amide hydrolase (FAAH) inhibitor
  138. A4374 PF-3845 FAAH ihibitor,highly potent and selective
  139. A4338 Rivaroxaban Factor Xa inhibitor
  140. B3234 Betrixaban Factor Xa inhibitor
  141. A4344 Ozagrel Thromboxane A2 synthetase inhibitor
  142. A4371 Ferrostatin-1 (Fer-1) Ferroptosis inhibitor, erastin-induced
  143. B4987 Liproxstatin-1 A potent ferroptosis inhibitor
  144. A3552 Levomefolate calcium Artificial form of folate
  145. A2489 Leucovorin Calcium Derivative of folic acid
  146. B1108 Ro 28-1675 Glucokinase activator
  147. B2160 LY2608204 GK activator
  148. A3369 DMP 777 Leukocyte elastase (HLE) inhibitor
  149. B1124 Pitavastatin HMG-CoA reductase inhibitor
  150. A8522 Simvastatin (Zocor) HMGCR (HMG-CoA reductase) inhibitor
  151. A8504 Pitavastatin Calcium Enzyme HMGCR inhibitor
  152. A3419 Fluvastatin HMGCR inhibitor
  153. A4363 Fluvastatin Sodium HMG-CoA reductase inhibitor
  154. A4365 Lovastatin HMG-CoA reductase inhibitor
  155. A4367 Atorvastatin Calcium HMG-CoA reductase inhibitor
  156. A4369 Pravastatin sodium HMG-CoA reductase inhibitor,highly selective and competitive
  157. B1125 Pravastatin HMG-CoA reductase inhibitor against sterol synthesis
  158. B1123 Rosuvastatin Competitive inhibitor of HMG-CoA reductase
  159. B1788 Mevastatin HMG-CoA reductase inhibitor
  160. A2213 17-DMAG (Alvespimycin) HCl Hsp90 inhibitor
  161. A3756 Retaspimycin HSP90 inhibitor,antiproliferative and antineoplastic
  162. A3739 PU-H71 Hsp90 inhibitor,potent and selective
  163. A3161 Alvespimycin Hsp90 inhibitor,potent and selective
  164. A4068 SNX-2112 Hsp90 inhibitor,ATP-competitve,potent and selective
  165. A4065 PF-04929113 (SNX-5422) Hsp90 inhibitor,potent and selective
  166. A4056 AT13387 Hsp90 inhibitor
  167. A4057 AUY922 (NVP-AUY922) Top Seller Potent Hsp90 inhibitor
  168. A4058 BIIB021 Hsp90 inhibitor,selective and competitive
  169. A4060 Geldanamycin Hsp90 inhibitor,potent and specific
  170. A4061 IPI-504 (Retaspimycin hydrochloride) Hsp90 inhibitor,novel, potent,selective
  171. A4062 KW-2478 Potent Hsp90 inhibitor, novel, non-ansamycin,
  172. A4064 NVP-BEP800 Oral Hsp90β inhibitor, novel, fully synthetic
  173. B5885 PU-WS13 Grp94-specific Hsp90 inhibitor
  174. A3109 17-AAG Hydrochloride Hsp90 inhibitor,geldanamycin analogue
  175. A4388 XL-888 Hsp90 inhibitor
  176. A4385 Ganetespib (STA-9090) Top Seller Hsp90 inhibitor,non-geldanamycin
  177. A4386 Elesclomol (STA-4783) Oxidative stress/apoptosis inducer,potent and novel
  178. A4054 17-AAG (KOS953) Top Seller Hsp90 inhibitor
  179. A4387 VER 155008 HSP 70 inhibitor,adenosine-derived
  180. B4571 CH5138303 Hsp90 inhibitor, orally available
  181. A4067 Radicicol ATPase/kinase inhibitor
  182. A4063 MPC-3100 Hsp90 inhibitor
  183. B3592 VER-50589 HSP90 inhibitor, potent
  184. B3693 NMS-E973 Hsp90 inhibitor,potent and selective
  185. B3593 VER-49009 HSP90 inhibitor, potent and selective
  186. A4373 NLG919 Potent IDO pathway inhibitor
  187. A3483 IDO inhibitor 1 Indoleamine-2,3-dioxygenase inhibitor
  188. B6036 INCB-024360 potent and selective inhibitor of IDO1
  189. B4900 Indoximod (NLG-8189) Indoleamine 2,3-dioxygenase (IDO) pathway inhibitor Potent and selective HDAC6 inhibitor
  190. A3493 INCB024360 analogue potent and selective inhibitor of IDO1
  191. A3358 Deltarasin KRAS-PDEδ interaction inhibitor
  192. B5841 AMG-47A destabilizer of the KRAS oncoprotein
  193. B1261 Deltarasin hydrochloride inhibitor of KRAS-PDEδ interaction, potent and selective
  194. B5616 GPBAR-A agonist of bile acid receptor GPBAR1
  195. B7794 BMS 309403 FABP4 inhibitor,potent and selective
  196. B6064 Myriocin immunosuppressant and specific serine palmitoyltransferase inhibitor
  197. B6095 RSL3 glutathione peroxidase 4 inhibitor
  198. B6155 Lauric Acid saturated medium-chain fatty acid
  199. B5599 Fatostatin A sterol regulatory element binding protein (SREBP) inhibitor
  200. B7608 SC 26196 Δ6 desaturase inhibitor
  201. B6967 R 59-022 Diacylglycerol (DAG) kinase inhibitor

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