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Metabolism

  1. Cat.No. Product Name Information
  2. B4750 (-)-p-Bromotetramisole Oxalate ALP inhibitor, potent and non-specific
  3. A8703 Isosafrole A stiripentol analog, a potent LDH inhibitor.
  4. A8704 Stiripentol An LDH inhibitor
  5. A4300 GW9662 PPARγ antagonist
  6. A3152 Aleglitazar PPARα/PPARγagonist
  7. A3216 Balaglitazone PPAR-γ partial agonist
  8. A3453 GW1929 Potent PPARγ agonist
  9. A3498 Inolitazone PPARgamma agonist
  10. A3893 Troglitazone Selective PPARγ agonist
  11. A4324 Pioglitazone HCl PPARγ agonist
  12. A4310 Rosiglitazone HCl PPARγ agonist
  13. A4301 T0070907 Human PPARγ antagonist,potent and selective
  14. A4302 Rosiglitazone maleate PPARγ agonist,high-affinity and selective,potent insulin sensitizer
  15. A4303 GSK3787 PPARβ/δ antagonist,novel and irreversible
  16. A4304 Rosiglitazone Potent PPARγ agonist
  17. A4305 WY-14643 (Pirinixic Acid) PPARα agonist,selective and highly potent
  18. A4306 Ciprofibrate PPARα agonist
  19. A4307 GW0742 PPARδ/β agonist,potent and selective
  20. A4309 GW501516 PPARβ agonist,selective and potent
  21. B6128 Fenofibric acid ppar inhibitor, lipid-lowering agent
  22. C3407 GQ-16 partial agonist for PPARγ
  23. C3544 BMS 687453 PPARα agonist
  24. C3986 Muraglitazar dual agonist of PPARα and PPARγ
  25. C4758 Darglitazone PPARγ agonist with antidiabetic actions
  26. C4916 GW 590735 potent and selective agonist of PPARα
  27. C4735 N-Octadecyl-N'-propyl-sulfamide activator of PPARα
  28. C4892 MCC-555 thiazolidinedione class anti-diabetic compound,a novel PPARα/γ dual ligand
  29. C5151 Cetaben unique,PPARα-independent peroxisome proliferator
  30. A8957 AUDA Potent epoxide hydrolase inhibitor/PPARα activator
  31. B5581 SR 1664 inhibits Cdk5-mediated PPARγ phosphorylation, antidiabetic agent
  32. B7010 15-deoxy-Δ-12,14-Prostaglandin J2 PPARγ agonist
  33. A3536 L-165041 PPARβ/δ agonist,cell permeable,potent and selective
  34. A3499 Inolitazone dihydrochloride PPARγ agonist,high-affinity and novel
  35. B6681 Ciglitazone PPARγ agonist
  36. B6691 BADGE PPARγ antagonist
  37. B6826 GW 7647 PPARα agonist
  38. B6929 SR 202 PPAR antagonist
  39. B6955 nTZDpa PPARγ partial agonist
  40. B7406 GSK 0660 PPARδ antagonist
  41. B7609 CP 775146 PPARα agonist
  42. B7553 Tesaglitazar Dual-specificity PPARα/γ agonist
  43. B7471 S26948 PPARγ agonist
  44. B2117 Pioglitazone PPAR agonist
  45. B1943 Fenofibrate PPARα agonist
  46. B1947 Gemfibrozil PPARα activator
  47. B3610 Clofibrate PPAR agonist
  48. B1195 Finasteride acetate 5α-reductase inhibitor
  49. A5143 Finasteride Inhibitor of Type II 5α-reductase
  50. A1659 Dutasteride 5-alpha-reductase inhibitor
  51. A5384 Zileuton 5-lipoxygenase (5-LOX) inhibitor, orally active
  52. B1207 Zileuton sodium 5-lipoxygenase and leukotrienes inhibitor
  53. B3422 U-73122 inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase)
  54. A2486 Malotilate Stimulates hepatocyte regeneration
  55. C4371 BW 755C dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways
  56. C4199 HZ52 5-lipoxygenase inhibitor
  57. C3794 1-Naphthyl 3,5-dinitrobenzoate dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor
  58. C3091 11-keto-β-Boswellic Acid leukotriene synthesis inhibitor via 5-lipoxygenase
  59. C3055 3-acetyl-11-keto-β-Boswellic Acid 5-lipoxygenase inhibitor
  60. C4696 Ebselen
  61. A3277 Capadenoson Adenosine A1 receptor agonist
  62. B5619 1-Deazaadenosine adenosine deaminase inhibitor
  63. B6662 EHNA hydrochloride cGMP-stimulated phosphodiesterase (PDE2) and adenosine deaminase inhibitor
  64. A4355 Tosedostat (CHR2797) Aminopeptidase inhibitor
  65. A1718 Posaconazole Sterol C14ɑ demethylase inhibitor
  66. B1225 Posaconazole hydrate C14ɑ demethylase inhibitor
  67. A4359 Brinzolamide CA II inhibitor
  68. A4360 Topiramate GluR5 receptor antagonist,anticonvulsant
  69. A4358 U-104 CAIX inhibitor
  70. A4357 Dorzolamide HCl Carbonic anhydrase inhibitor
  71. A4364 Methazolamide Carbonic anhydrase inhibitor
  72. A4362 Tioxolone CAI inhibitor
  73. B6125 Acetazolamide carbonic anhydrase (CA) inhibitor
  74. B6154 Benzenesulfonamide carbonic anhydrase inhibitor
  75. A4378 Torcetrapib CETP inhibitor
  76. A4375 Anacetrapib (MK-0859) RhCETP/mutant CETP(C13S) inhibitor
  77. A4376 Dalcetrapib (JTT-705, RO4607381) rhCETP inhibitor
  78. A4377 Evacetrapib (LY2484595) CETP inhibitor,potent and selective
  79. A8430 Ezetimibe Cholesterol transport inhibitor
  80. A3404 Etomoxir (CPT)-1 and DGAT activity inhibitor
  81. C4945 Perhexiline (maleate) CPT1 and CPT2 inhibitor
  82. A4313 Cobicistat (GS-9350) Selective CYP3A inhibitor
  83. C4691 4-phenyl-1,2,3-Thiadiazole selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1)
  84. C4880 6,7-dihydroxy Bergamottin potent inhibitor of CYP3A4
  85. B5990 Diosmetin CYP1A1 inhibitor
  86. B5963 7-Ethoxyresorufin Specific subtrate of CYP1A
  87. B5405 YM 511 aromatase (CYP19) inhibitor
  88. B7714 3-Cyano-7-ethoxycoumarin Fluorescent P450 substrate
  89. A4320 Voriconazole CYP51 inhibitor
  90. A4322 Clarithromycin CYP3A inhibitor, potent
  91. A3374 Dronedarone CYP3A4 and 2D6 inhibitor,moderate
  92. B7737 ABT Cytochrome P450 inhibitor
  93. B6768 TMS cytochrome P450 1B1 inhibitor
  94. B5724 Pentoxyresorufin fluorometric cytochrome P450 substrate
  95. B5723 Methoxyresorufin fluorometric substrate of cytochrome P450
  96. B4683 VT-464 Human CYP17 lyase inhibitor
  97. B4685 VT-464 racemate CYP17 lyase inhibitor
  98. B4684 VT-464 R enantiomer CYP17 lyase inhibitor
  99. B4692 Dafadine-A DAF-9 cytochrome P450 inhibitor
  100. A4336 Mycophenolate Mofetil IMPDH inhibitor
  101. A4351 PluriSIn #1 (NSC 14613) Top Seller SCD1 inhibitor
  102. A4348 Trilostane 3β-HSD inhibitor
  103. A4342 Gimeracil Dihydropyrimidine dehydrogenase inhibitor
  104. A4339 AGI-5198 Top Seller IDH1 inhibitor against R132 mutant,selective and cell-permeable
  105. B6124 Fomepizole competitive inhibitor of the enzyme alcohol dehydrogenase
  106. B7804 AG-221 (Enasidenib) mutant isocitrate dehydrogenase 2 (IDH2) inhibitor
  107. B7805 AG-120 mutant IDH1 inhibitor
  108. B7824 ML390 human DHODH inhibitor
  109. C3039 STK393606 competitive inhibitor of NAD+-dependent type-I 15-hydroxy PGDH
  110. C3535 Piericidin A mitochondrial complex I inhibitor
  111. C3853 NCT-503 3-phosphoglycerate dehydrogenase (PHGDH) inhibitor
  112. C4497 6-Aminonicotinamide 6-phosphogluconate dehydrogenase inhibitor
  113. C4671 Inosine-5'-monophosphate (sodium salt hydrate) substrate of IMP dehydrogenase (IMPDH)
  114. C4845 PHGDH-inactive inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 and NCT-503
  115. A1606 L-a-Hydroxyglutaric acid disodium salt salt form of L-α-Hydroxyglutaric acid
  116. A3837 DL-α-Hydroxyglutaric acid disodium salt alpha hydroxy acid
  117. B6104 BVT 2733 11beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor
  118. A4333 CPI-613 PDH/α-KGDH inhibitor
  119. A3146 AGI-6780 IDH2/R140Q mutation inhibitor
  120. B4669 Vidofludimus DHODH inhibitor
  121. B7725 Methylmalonate reversible succinate dehydrogenase inhibitor
  122. B5697 WIN 18446 inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)
  123. B5716 Galloflavin human lactate dehydrogenase (LDH) inhibitor
  124. B5354 CGP 3466B maleate GAPDH inhibitor
  125. B5508 Alda 1 ALDH2 activator
  126. B5643 TC HSD 21 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor
  127. B5799 Qc 1 threonine dehydrogenase (TDH) inhibitor
  128. A8721 CBR-5884 selective inhibitor of PHGDH
  129. B4929 GSK 2837808A Potent, selective lactate dehydrogenase A (LDHA) inhibitor
  130. B4928 CVT 10216 reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2)
  131. B1129 Mutant IDH1 inhibitor Potent mutant IDH1 R132H inhibitor
  132. A4353 Pyrimethamine DHFR inhibitor
  133. A4347 Methotrexate Folate antagonist,inhibits DFHR
  134. A4350 Pralatrexate Antifolate,a folate analog
  135. A3707 Pemetrexed disodium hemipenta hydrate Antifolate and antimetabolite agent
  136. A4390 Pemetrexed Top Seller TS, DHFR,GARFT and AICARFT inhibitor
  137. A3215 AZD7687 DGAT inhibitor,potent and selective
  138. A3542 LCQ-908 DGAT1 inhibitor
  139. A3364 DGAT-1 inhibitor 2 Antiobesity agents
  140. A3363 DGAT-1 inhibitor Diacylglycerol acyltransferase (DGAT1) inhibitor
  141. A3140 ABT-046 DGAT-1 inhibitor,potent and selective
  142. B4944 AZD 3988 diacylglycerol acyltransferase (DGAT-1) inhibitor
  143. C4872 Amidepsine A DGAT inhibitor
  144. C4875 Amidepsine D DGAT inhibitor
  145. B4822 DGAT1-IN-1 potent DGAT1 inhibitor
  146. A4335 Mildronate GBB hydroxylase inhibitor
  147. A4332 Nepicastat (SYN-117) HCl Dopamine-β-hydroxylase inhibitor
  148. A4330 Isotretinoin Dopamine β-hydroxylase activator
  149. A4015 Disulfiram Dopamine β-hydroxylase inhibitor
  150. B7346 PF 915275 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor
  151. B3588 AP-III-a4 enolase inhibitor
  152. B5714 SA 47 FAAH inhibitor
  153. B5704 SA 57 FAAH inhibitor
  154. B5562 TC-F 2 FAAH inhibitor
  155. B7701 JZL 195 Dual inhibitor of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL)
  156. B7356 PF 750 FAAH inhibitor
  157. A3714 PF-04457845 FAAH inhibitor,potent and exquisitely selective
  158. A3571 LY2183240 Blocker of anandamide uptake,highly potent
  159. A4372 URB597 FAAH inhibitor,potent and selective
  160. A4361 JNJ-1661010 FAAH inhibitor,potent and selective
  161. C4983 JP83 irreversible fatty acyl amide hydrolase (FAAH) inhibitor
  162. C4756 PF-622 potent, time-dependent, irreversible FAAH inhibitor
  163. C4279 4-(n-nonyl) Benzeneboronic Acid FAAH and MAGL inhibitor
  164. C4251 Oleoyl Ethyl Amide FAAH inhibitor with potential analgesic and anxiolytic activity
  165. C4122 JNJ-42165279 FAAH inhibitor
  166. B4931 TAK 21d Potent FAAH inhibitor
  167. B1245 FAAH inhibitor 1 Potent fatty acid amide hydrolase (FAAH) inhibitor
  168. A4374 PF-3845 FAAH ihibitor,highly potent and selective
  169. A4338 Rivaroxaban Factor Xa inhibitor
  170. A4344 Ozagrel Thromboxane A2 synthetase inhibitor
  171. B3234 Betrixaban Factor Xa inhibitor
  172. A4371 Ferrostatin-1 (Fer-1) Ferroptosis inhibitor, erastin-induced
  173. B4987 Liproxstatin-1 A potent ferroptosis inhibitor
  174. A3552 Levomefolate calcium Artificial form of folate
  175. A2489 Leucovorin Calcium Derivative of folic acid
  176. B1108 Ro 28-1675 Glucokinase activator
  177. B2160 LY2608204 GK activator
  178. A3369 DMP 777 Leukocyte elastase (HLE) inhibitor
  179. B1124 Pitavastatin HMG-CoA reductase inhibitor
  180. A8522 Simvastatin (Zocor) HMGCR (HMG-CoA reductase) inhibitor
  181. A8504 Pitavastatin Calcium Enzyme HMGCR inhibitor
  182. A3419 Fluvastatin HMGCR inhibitor
  183. A4363 Fluvastatin Sodium HMG-CoA reductase inhibitor
  184. A4365 Lovastatin HMG-CoA reductase inhibitor
  185. A4367 Atorvastatin Calcium HMG-CoA reductase inhibitor
  186. A4369 Pravastatin sodium HMG-CoA reductase inhibitor,highly selective and competitive
  187. C4030 (3S,5S)-Atorvastatin (sodium salt) negetive control of Atorvastatin, HMG-CoA reductase inhibitor
  188. C4426 Simvastatin (sodium salt) HMG-CoA reductase inhibitor
  189. B1123 Rosuvastatin Competitive inhibitor of HMG-CoA reductase
  190. B1125 Pravastatin HMG-CoA reductase inhibitor against sterol synthesis
  191. B1788 Mevastatin HMG-CoA reductase inhibitor
  192. A4057 AUY922 (NVP-AUY922) Top Seller Potent Hsp90 inhibitor
  193. A2213 17-DMAG (Alvespimycin) HCl Hsp90 inhibitor
  194. A3756 Retaspimycin HSP90 inhibitor,antiproliferative and antineoplastic
  195. A3739 PU-H71 Hsp90 inhibitor,potent and selective
  196. A3161 Alvespimycin Hsp90 inhibitor,potent and selective
  197. A4068 SNX-2112 Hsp90 inhibitor,ATP-competitve,potent and selective
  198. A4065 PF-04929113 (SNX-5422) Hsp90 inhibitor,potent and selective
  199. A4060 Geldanamycin Hsp90 inhibitor,potent and specific
  200. A4058 BIIB021 Hsp90 inhibitor,selective and competitive
  201. A4056 AT13387 Hsp90 inhibitor

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