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JNK

JNK (c-Jun N-terminal kinase) is a group of kinases belong to the mitogen-activated protein kinase family and also play a role in T cell differentiation and the cellular apoptosis pathway.

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  1. Cat.No. Product Name Information
  2. B9007 c-JUN peptide
  3. A4604 SP 600125 SP600125 is a selective, reversible and ATP-competitive inhibitor of Jun N-terminal kinase (JNK) with IC50 values of 40, 40 and 90 nM for JNK1, 2 and 3, respectively .
  4. A3520 JNK-IN-8 JNK-IN-8 is a highly selective JNK inhibitor based on multiple profiling strategies. JNK-IN-8 inhibits c-Jun phosphorylation at submicromolar concentrations in cells.
  5. A3519 JNK-IN-7 JNK-IN-7 is a selective JNK inhibitor with IC50 values of 1.54 nM, 1.99 nM, 0.75 nM to JNK1, JNK2, JNK3, respectively.
  6. A3353 DB07268 DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.
  7. A3288 CC-930 CC-930 is a potent and selective inhibitor of JNK1/JNK2/JNK3 with IC50 values of 61 nM, 7 nM and 6 nM respectively.
  8. A3287 CC-401 hydrochloride CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity.
  9. A3189 AS 602801 c-Jun N-terminal kinase (JNKs) plays a critical role in a wide range of diseases including cell death (apoptosis)-related disorders and inflammatory disorders.
  10. C5106 LL-Z 1640-4
  11. B5960 PF-03394197(Oclacitinib)

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