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Topoisomerase

Topoisomerase are enzymes that regulate the overwinding or underwinding of DNA.

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  1. Cat.No. Product Name Information
  2. A8532 Teniposide Teniposide is a glycoside-derivative of podophyllotoxin.
  3. A5511 Ofloxacin Ofloxacin is a fluorinated quinolone antibacterial.
  4. A5323 Moxifloxacin HCl Moxifloxacin HCl is anti-infective compound with a broad antibacterial spectrum.[1]
  5. A1602 Dexrazoxane HCl (ICRF-187, ADR-529) Dexrazoxane hydrochloride is a cardioprotective agent.
  6. A5133 Irinotecan (+)-Irinotecan is an isomer of the Topo I inhibitor Irinotecan.
  7. A2451 Epirubicin HCl Epirubicin is an inhibitor of DNA topoisomerase (TOPII) .
  8. A2782 Amonafide Amonafide is a DNA intercalator and Topo II (topoisomerase II) inhibitor for the treatment of neoplastic diseases.
  9. A2476 Idarubicin HCl Idarubicin is an inhibitor of DNA topoisomerase II .
  10. A1971 Etoposide Etoposide (VP-16) is the first agent recognized as a topoisomerase II inhibitor of anticancer drug with IC50 of 59.2 μM.
  11. A2306 Ellagic acid Selective, ATP-competitive inhibitor of casein kinase 2 (CK2) (IC50 values are 40, 2900, 3500, 4300 and 9400 nM for CK2, Lyn, PKA, Syk?and FGR respectively).

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