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HDAC

Histone deacetylases (HDACs), known for their ability to target histones as well as more than 50 non-histone proteins, are classified into three major classes according to their homology to yeast proteins, including class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC7 and HDAC9) and class IV (HDAC11). HDAC inhibitors, a large group of compounds that is able to induce the accumulation of acetylated histones as well as non-histone proteins, are divided into several structural classes including hydroxamates, cyclic peptides, aliphatic acids and benzamides. HDAC inhibitors have been investigated for their efficacy as anticancer agents in the treatment of a wild range of cancers.

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Biochemicals

  1. Cat.No. Product Name Information
  2. B1251 Valproic acid HDAC1 inhibitor
  3. A4495 NCH 51 Histone deacetylase (HDAC) inhibitor
  4. A4493 KD 5170 HDAC inhibitor
  5. A3860 Tasquinimod Antiangiogenic and antineoplastic agent
  6. A3761 RG2833 Brain-penetrant HDAC inhibitor
  7. A3755 Resminostat hydrochloride HDAC inhibitor
  8. A3348 Daminozide KDM2A inhibitor
  9. A3305 CHAPS Zwitterionic detergent for membrane proteins,nondenaturing
  10. A4105 M344 Top Seller HDAC inhibitor,potent and cell-permeable
  11. A4104 AR-42 (OSU-HDAC42) Top Seller HDAC inhibitor,novel and potent
  12. A4103 LAQ824 (NVP-LAQ824,Dacinostat) HDAC inhibitor,potent and novel
  13. A4496 NSC 3852 HDAC inhibitor
  14. A4497 Pyroxamide HDAC1 inhibitor
  15. B1141 Varenicline Hydrochloride α4β2 nicotinic receptor agonist
  16. A8806 TMP269 HDAC 4/5/7/9 inhibitor
  17. A8803 RGFP966 Specific HDAC3 inhibitor
  18. A9906 HDAC Set I For inhibiting HDAC
  19. A8547 Tubastatin A HCl Top Seller HDAC6 inhibitor,potent and selective
  20. A4500 TCS HDAC6 20b Selective HDAC6 inhibitor
  21. A4498 SBHA HDAC1/HDAC3 inhibitor,cell-permeable
  22. A4494 LMK 235 HDAC4/HDAC5 inhibitor
  23. A4501 Tubacin HDAC6 inhibitor,potent,selective,reversible,cell-permeable
  24. A4499 TC-H 106 HDAC inhibitor
  25. A4102 CI994 (Tacedinaline) Top Seller HDAC inhibitor
  26. A4101 Tubastatin A HDAC6 inhibitor,potent and selective
  27. A4090 JNJ-26481585 Top Seller Potent HDAC inhibitor
  28. A4089 Mocetinostat (MGCD0103, MG0103) Top Seller HDAC inhibitor,isotype-selective and potent
  29. A4084 Vorinostat (SAHA, MK0683) Top Seller HDAC inhibitor
  30. A4083 Rocilinostat (ACY-1215) Top Seller Selective HDAC6 inhibitor
  31. N1315 Parthenolide Parthenolide is a sesquiterpene lactone and active principle of feverfew (Chrysanthemum parthenium)
  32. A8176 Apicidin Potent HDAC inhibitor
  33. A8173 Romidepsin (FK228, depsipeptide) Top Seller HDAC1/HDAC2 inhibitor,potent and selective
  34. A8183 Trichostatin A (TSA) Top Seller HDAC inhibitor
  35. A8178 Panobinostat (LBH589) Top Seller HDAC inhibitor
  36. A8171 Entinostat (MS-275,SNDX-275) Top Seller HDAC1 and HDAC3 inhibitor
  37. A4091 PCI-34051 HDAC8 inhibitor,potent and selective
  38. A4092 CUDC-101 Multitargeted HDAC inhibitor
  39. A4093 ITF2357 (Givinostat) Top Seller HDAC inhibitor
  40. A4100 Droxinostat Selective HDAC inhibitor
  41. A4099 Valproic acid sodium salt (Sodium valproate) HDAC inhibitor
  42. A4098 PCI-24781 (CRA-024781) Pan-HDAC inhibitor
  43. A4097 CUDC-907 Potent PI3K/HDAC inhibitor
  44. A4096 Belinostat (PXD101) Hydroxamate-type HDAC inhibitor
  45. A4095 Pracinostat (SB939) Top Seller Pan-HDAC inhibitor
  46. A4094 MC1568 Top Seller Class II HDAC inhibitor,potent and selective
  47. A4108 Resminostat (RAS2410) Potent HDAC inhibitor
  48. A4107 Sodium Phenylbutyrate Histone deacetylase inhibitor
  49. A4106 Scriptaid Top Seller HDAC inhibitor,novel and cell-permeable
  50. C4305 HNHA HDAC inhibitor
  51. C3606 Nullscript negative control of scriptaid, HDAC inhibitor
  52. B5882 ORY-1001 Selective inhibitor of KDM1A.
  53. B4988 BRD73954 potent and selective HDAC inhibitor
  54. B4856 CAY10603 potent and selective inhibitor of HDAC6
  55. B4794 Santacruzamate A (CAY10683) HDAC inhibitor, potent and selective
  56. C4327 CBHA HDAC inhibitor