Toggle Nav

DiscoveryProbe™ Immunology/Inflammation-related Compounds Panel

In stock
Catalog No.
Grouped product items
SizePriceStock Qty
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors


A wide range of well-characterized bioactive molecules that covers various targets related to immunology/inflammation, including TLR, PLA2 and NF-κB etc. Facilitate your research towards the insights of cancer, inflammatory and autoimmune diseases etc. Applicable in cellular assays, animal models and drug screenings etc.


Available in stock with overnight delivery and free shipping over $500 Cost-effective and competitive price to save your findings Potent, selective and cell-permeable in inhibiting or activating target molecules Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.) Detailed files describing potency, selectivity and applications etc. Supported by published data from top peer-reviewed journals Guaranteed high quality with NMR and HPLC validation

Featured Products of the Panel

Catalog No. Product Name Summary Targets CAS Number Smiles
A3850 TAK-242 TLR 4 signaling inhibitor Immunology/Inflammation|TLR 243984-11-4 CCOC(=O)C1=CCCCC1S(=O)(=O)NC2=C(C=C(C=C2)F)Cl
A3248 BMS-345541 IKK inhibitor,highly selective NF-κB|IκB/IKK 547757-23-3 CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN.Cl
A3628 MLN120B IκB Kinase β Inhibitor NF-κB|IκB/IKK 783348-36-7 CC1=C(C=CC=N1)C(=O)NC2=C3C(=CC(=C2OC)Cl)C4=C(N3)C=NC=C4
B1585 SC-514 ATP-competitive IKK-2 inhibitor, orally active NF-κB|IκB/IKK 354812-17-2 C1=CSC=C1C2=CC(=C(S2)C(=O)N)N
B3033 Bay 11-7085 NK-κB activation inhibitor NF-κB|IκB/IKK 196309-76-9 CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)C=CC#N
N1855 Andrographolide NF-κB signaling Inhibitor NF-κB|IκB/IKK 5508-58-7 CC12CCC(C(C1CCC(=C)C2CC=C3C(COC3=O)O)(C)CO)O
A3891 Triptolide IL-2/MMP-3/MMP7/MMP19 inhibitor NF-κB|NF-κB 38748-32-2 CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2O)O7)COC6=O)C
A4217 QNZ (EVP4593) Potent NF-κB inhibitor NF-κB|NF-κB 545380-34-5 C1=CC=C(C=C1)OC2=CC=C(C=C2)CCNC3=NC=NC4=C3C=C(C=C4)N
Download the Immunology/Inflammation-related Compounds Panel - XLSX       Download the Immunology/Inflammation-related Compounds Panel - SDF


1. Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity. 2011 May 27;34(5):637-50.
TLR(Toll-like receptor)-mediated recognition of components derived from a wide range of pathogens and their role in the subsequent initiation of innate immune responses is widely accepted; however, the recent discovery of non-TLR PRRs(pattern recognition receptors), such as C-type lectin receptors, NOD-like receptors, and RIG-I-like receptors, suggests that many aspects of innate immunity are more sophisticated and complex. In this review, we will focus on the role played by TLRs in mounting protective immune responses against infection and their crosstalk with other PRRs with respect to pathogen recognition.