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BS-181 HCl |
highly selective CDK7 inhibitor |
Sample solution is provided at 25 µL, 10mM.
Quality Control & MSDS
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
| Description | BS-181 HCl is a highly selective inhibitor of CDK7 with an IC50 value of 21 nM. | |||||
| Targets | CDK7 | |||||
| IC50 | 21 nM | |||||
BS-181 HCl Dilution Calculator
BS-181 HCl Molarity Calculator
| Cas No. | 1397219-81-6 | SDF | Download SDF |
| Chemical Name | 5-N-(6-aminohexyl)-7-N-benzyl-3-propan-2-ylpyrazolo[1,5-a]pyrimidine-5,7-diamine;hydrochloride | ||
| Canonical SMILES | CC(C)C1=C2N=C(C=C(N2N=C1)NCC3=CC=CC=C3)NCCCCCCN.Cl | ||
| Formula | C22H32N6.HCl | M.Wt | 416.99 |
| Solubility | Soluble in DMSO > 10 mM | Storage | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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BS-181 is a small molecule inhibitor which is highly selective for cyclin-dependent kinase 7 (Cdk7) activity (IC50 = 21 nM). In a cell-free environment, BS-181 displays more potent activity than Roscovitine , and shows high inhibitory selectivity for Cdk7
