Search Site
Related Products

BS-181 HCl

highly selective CDK7 inhibitor

BS-181 HCl

Catalog No. A5700
Size Price Stock Qty
5mg $200.00 In stock
25mg $480.00 In stock
100mg $1,000.00 In stock

Tel: +1-832-696-8203

Email: sales@apexbt.com

Worldwide Distributors

Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

BS-181 HCl

Biological Activity

Description BS-181 HCl is a highly selective inhibitor of CDK7 with an IC50 value of 21 nM.
Targets CDK7          
IC50 21 nM          

BS-181 HCl Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

BS-181 HCl Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Chemical Properties

Cas No. 1397219-81-6 SDF Download SDF
Chemical Name 5-N-(6-aminohexyl)-7-N-benzyl-3-propan-2-ylpyrazolo[1,5-a]pyrimidine-5,7-diamine;hydrochloride
Canonical SMILES CC(C)C1=C2N=C(C=C(N2N=C1)NCC3=CC=CC=C3)NCCCCCCN.Cl
Formula C22H32N6.HCl M.Wt 416.99
Solubility Soluble in DMSO Storage Store at -20°C
Shipping Condition: Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

BS-181 is a small molecule inhibitor which is highly selective for cyclin-dependent kinase 7 (Cdk7) activity (IC50 = 21 nM). In a cell-free environment, BS-181 displays more potent activity than Roscovitine , and shows high inhibitory selectivity for Cdk7