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VEGFR

VEGFR are receptors for vascular endothelial growth factor and belong to receptor tyrosine kinases.

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  1. Brivanib (BMS-540215)
    A2597 Brivanib (BMS-540215)
    Target: VEGFR|FGFR|Flk1
    Summary: VEGFR-2 inhibitor,ATP-competitive
      insoluble in H2O; ≥18.5 mg/mL
  2. Lenvatinib (E7080)
    A2174 Lenvatinib (E7080)
    Target: VEGFR|PDGFR|RET
    Summary: VEGFR inhibitor
      ≥21.35 mg/mL
  3. MGCD-265
    A5057 MGCD-265
    Target: VEGFR|c-MET
    Summary: Met/Flt/Flk/Ron/Tie-2 inhibitor
      ≥25.9 mg/mL
  4. Vatalanib (PTK787) 2HCl
    A1778 Vatalanib (PTK787) 2HCl
    Target: VEGFR
    Summary: Tyrosine kinase receptor inhibitor
      ≥21 mg/mL
  5. Ponatinib (AP24534)
    A5467 Ponatinib (AP24534)
     1 Citation
    Target: VEGFR|PDGFR|Bcr-Abl|FGFR|Src
    Summary: pan-BCR-ABL inhibitor,multi-kinase inhibitor
      ≥53.3 mg/mL
  6. RAF265
    A8313 RAF265
    Target: Raf|VEGFR
    Summary: Multiple intracellular kinases inhibitor
      ≥25.9 mg/mL
  7. Axitinib (AG 013736)
    A8370 Axitinib (AG 013736)
     1 Citation
    Target: VEGFR|PDGFR|c-Kit
    Summary: VEGFR1/ c-Kit inhibitor
      insoluble in H2O; ≥19.3 mg/mL
  8. Telatinib (BAY 57-9352)
    A8550 Telatinib (BAY 57-9352)
    Target: VEGFR|PDGFR|c-Kit
    Summary: VEGFR-2/-3,PDGFR-β and c-Kit inhibitor
      insoluble in H2O; insoluble in EtOH; ≥20.5 mg/mL
  9. Vandetanib (ZD6474)
    A8555 Vandetanib (ZD6474)
    Target: VEGFR|EGFR
    Summary: VEGFR2/EGFR antagonist
      insoluble in H2O; ≥11.88 mg/mL
  10. CP-673451
    B2173 CP-673451
    Target: PDGFR
    Summary: PDGFRα/β inhibitor,potent and selective

Items 11-20 of 30

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