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Bcr-Abl

Bcl-Abl is a constitutively activated chimeric tyrosine kinase which is the genetic abnormality expressed in patient with CML (chronic myeloid leukemia).

3 Items

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  1. Imatinib Mesylate (STI571)
    A1805 Imatinib Mesylate (STI571)
    Target: PDGFR|c-Kit|Bcr-Abl
    Summary: Abl/c-kit/PDGFR inhibitor
      ≥29.5 mg/mL
  2. Ponatinib (AP24534)
    A5467 Ponatinib (AP24534)
     1 Citation
    Target: VEGFR|PDGFR|Bcr-Abl|FGFR|Src
    Summary: pan-BCR-ABL inhibitor,multi-kinase inhibitor
      ≥53.3 mg/mL
  3. Dasatinib Monohydrate
    B5954 Dasatinib Monohydrate
    Target: PDGFR|c-Kit|Bcr-Abl|Src
    Summary: Inhibitor of ABL, SRC, KIT, PDGFR, and other tyrosine kinases.
      ≥25.3 mg/mL

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  1. Selective1 item
Related Disease
  1. Leukemia1 item