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PDE

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

Items 11-16 of 16

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  1. Sildenafil
    A3817 Sildenafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor, selective
      ≥22.65 mg/mL
  2. Vinpocetine
    B2276 Vinpocetine
    Target: Phosphodiesterases (PDEs)
    Summary: PDE inhibitor
      ≥2.59 mg/mL
  3. Milrinone
    B1386 Milrinone
    Target: Phosphodiesterases (PDEs)
    Summary: PDE-3 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥8.2 mg/mL
  4. Etazolate hydrochloride
    B6304 Etazolate hydrochloride
     2 Citation
    Target: Phosphodiesterases (PDEs)
    Summary: PDE-4 inhibitor and selective GABA-A receptor modulator
      ≥7.75 mg/mL
  5. BRL 50481
    B6988 BRL 50481
    Target: Phosphodiesterases (PDEs)
    Summary: PDE7 inhibitor,potent and selective
      Soluble in DMSO
  6. Udenafil
    B3439 Udenafil
    Target: Phosphodiesterases (PDEs)
    Summary: PDE5 inhibitor
      insoluble in H2O; ≥117.2 mg/mL

Items 11-16 of 16

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