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Signaling Pathways

10 Items

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  1. Thioridazine HCl
    A8537 Thioridazine HCl
    Target: Cytochrome P450 (CYP450)|D1 and D5 Receptors|D2 Receptors|D3 Receptors|D4 Receptors
    Summary: Calcium channel protein inhibitor
  2. TOK-001
    A8623 TOK-001
    Target: Androgen Receptors|Cytochrome P450 (CYP450)
    Summary: CYP17 inhibitor and androgen receptor (AR) antagonist
      insoluble in H2O; ≥12.4 mg/mL
  3. 7-Ethoxyresorufin
    B5963 7-Ethoxyresorufin
    Target: Cytochrome P450 (CYP450)
    Summary: Specific subtrate of CYP1A
      Soluble in DMSO
  4. Rifabutin
    B2126 Rifabutin
    Target: Cytochrome P450 (CYP450)
    Summary: anti-TB(tuberculosis) medicine
      ≥42.35 mg/mL
  5. Fluconazole
    B2094 Fluconazole
    Target: Cytochrome P450 (CYP450)
    Summary: Triazole antifungal agent
      insoluble in H2O; ≥10.9 mg/mL
  6. Quinidine
    B7590 Quinidine
    Target: Voltage-gated Sodium (NaV) Channels|Cytochrome P450 (CYP450)
    Summary: reduces both Na+ and K+ channel currents
  7. Abiraterone acetate
    A8202 Abiraterone acetate
    Target: Cytochrome P450 (CYP450)
    Summary: Cytochrome p450 17a1 inhibitor
      insoluble in H2O; ≥11.22 mg/mL
  8. Cobicistat (GS-9350)
    A4313 Cobicistat (GS-9350)
    Target: Cytochrome P450 (CYP450)
    Summary: Selective CYP3A inhibitor
      insoluble in H2O; ≥150.9 mg/mL
  9. Ketoconazole
    A4316 Ketoconazole
    Target: Cytochrome P450 (CYP450)
    Summary: Inhibitor of cyclosporine oxidase and testosterone 6 beta-hydroxylase
      ≥23.4 mg/mL
  10. Zosuquidar
    A3956 Zosuquidar
    Target: P-glycoprotein (P-gp)|Cytochrome P450 (CYP450)
    Summary: MDR modulator
      Soluble in DMSO

10 Items

per page