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Signaling Pathways

Signaling Pathways

A4139 AG-490
3 Citation

Target: EGFR|JAK

Summary: JAK2/EGFR inhibitor

insoluble in H2O; ≥14.7 mg/mL
A4148 NVP-BSK805 2HCl

Target: JAK

Summary: JAK2 inhibitor

≥30.8 mg/mL
A4184 PFI-1 (PF-6405761)
1 Citation

Target: Bromodomains

Summary: BET inhibitor

insoluble in H2O; insoluble in EtOH; ≥128.4 mg/mL
A4123 KW 2449

Target: Aurora Kinases|FLT3|Bcr-Abl

Summary: Multikinase inhibitor

insoluble in EtOH; insoluble in H2O; ≥16.6 mg/mL
A4127 GSK1070916

Target: Aurora Kinases

Summary: Aurora B/C inhibitor

≥25.4 mg/mL
A1907 5-Azacytidine
6 Citation

Target: DNA Methyltransferases

Summary: DNA methyltransferase inhibitor.

insoluble in EtOH; ≥24.45 mg/mL
A4347 Methotrexate
2 Citation

Target: Folate Analogue

Summary: Folate antagonist,inhibits DFHR

≥21.55 mg/mL
A4381 FK866 (APO866)
1 Citation

Target: Nampt

Summary: NAMPT inhibitor, non-competitive, highly specific

insoluble in H2O; ≥19.6 mg/mL
A1933 Carfilzomib (PR-171)
10 Citation

Target: Proteasome

Summary: Proteasome inhibitor, epoxomicin analog

≥35.99 mg/mL
A3570 LY2090314

Target: GSK-3

Summary: Potent GSK-3 inhibitor

insoluble in H2O; ≥91 mg/mL