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Signaling Pathways

Signaling Pathways

B4660 PI-3065

Target: PI3K

Summary: P110δkinase inhibitor

≥22.7 mg/mL
A8210 GDC-0941
10 Citation

Target: PI3K

Summary: PI3K inhibitor,potent and selective

≥25.7 mg/mL
A8250 LY 294002
16 Citation

Target: PI3K

Summary: Potent PI3K inhibitor
A5112 XL147

Target: PI3K

Summary: PI3K inhibitor,selective and reversible

≥22.45 mg/mL
A2681 TGX-221

Target: PI3K

Summary: PI3Kβ inhibitor,potent,selective and ATP competitive

insoluble in H2O; insoluble in EtOH; ≥68.7 mg/mL
A1769 KU-0060648
1 Citation

Target: PI3K|DNA-PK

Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
A8315 NU7441 (KU-57788)
4 Citation

Target: PI3K|DNA-PK

Summary: DNA-PK inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
A8346 BYL-719
1 Citation

Target: PI3K

Summary: Selective PI3Kα inhibitor

≥22.07 mg/mL
A8353 3-Methyladenine
3 Citation

Target: PI3K

Summary: Class III PI3K inhibitor

≥5 mg/mL
A8556 GSK2126458
1 Citation

Target: PI3K|mTOR

Summary: PI3K/mTOR inhibitor

≥25.3 mg/mL